Page 247 - Pharmaceutics IV (02-06-01305)
P. 247
3/30/24
By
Prof Alyaa Ramadan
Fac of Pharmacy, Alex University
Prof Alyaa Ramadan, ceutics, AU
1
Advantages of pulmonary drug
delivery
• Relatively easy and convenient drug administration, low invasiveness
(selective, quick and painless )
• Local for treating pulmonary conditions.
• Systemic circulation through the alveoli
– Some drugs are not available as tablets as they are not absorbed orally,
such as sodium cromoglycate( avoidance of first pass effect and
degradation in GIT).
• Lipid soluble molecules are absorbed quickly (e.g bronchodilators,
corticosteroids, AB , antifungals.)
• Offer a route of administration for Macromolecules (enzymes and insulin)
Prof Alyaa Ramadan, ceutics, AU
2
1