Page 247 - Pharmaceutics IV (02-06-01305)
P. 247

3/30/24

                                                                                          By

                 Prof Alyaa Ramadan

                                        Fac of Pharmacy, Alex University

                                                                      Prof Alyaa Ramadan, ceutics, AU

1

    Advantages of pulmonary drug
                     delivery

     • Relatively easy and convenient drug administration, low invasiveness
         (selective, quick and painless )

     • Local for treating pulmonary conditions.
     • Systemic circulation through the alveoli

          – Some drugs are not available as tablets as they are not absorbed orally,
              such as sodium cromoglycate( avoidance of first pass effect and
              degradation in GIT).

     • Lipid soluble molecules are absorbed quickly (e.g bronchodilators,
         corticosteroids, AB , antifungals.)

     • Offer a route of administration for Macromolecules (enzymes and insulin)

                                                                      Prof Alyaa Ramadan, ceutics, AU

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