Page 28 - Pharmaceutics IV (02-06-01305)

Pharmaceutical requirements Sterility

Steam

• In general, it is applicable to pharmaceutical preparations and

materials that can withstand the required temperatures and are

penetrated but not adversely affected by moisture:

➢ Aqueous solutions in sealed containers, such as ampoules, are

readily sterilized by this method.

➢ Bulk solutions, glassware, surgical dressings, and

instruments.

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Pharmaceutical requirements

Sterility

Dry heat

• It is generally employed for substances that are not effectively

sterilized by moist heat:
➢ Oils, fats, glycerin, oleaginous preparations and any

preparations not penetrated by moisture
➢ Exposed powders
➢ Glassware and surgical instruments

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Salma E. EL-Habashy