Page 51 - Pharmaceutics IV (02-06-01305)
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Parenterals: Dosage forms
Injection (injectable solution)
• Route: given through any route of administration (aqueous solutions)
• Requirements: clear (free of particulate matter)
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Parenterals: Dosage forms
Injectable suspension
• For water-insoluble drugs
• Formulation concept & method:
➢ It is one of the most difficult parenteral dosage forms to formulate.
➢ Two basic methods are used to prepare parenteral suspensions:
(i) Sterile vehicle and powder are combined aseptically
(ii) Sterile solutions are combined, and the crystals are formed in situ
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Salma E. EL-Habashy