Page 152 - Pharm.Org.Chem-I 02-06-05-101

Aromaticity

• Ola Sami Afifi, PhD
• Lecturer of Pharmaceutical Chemistry
• Faculty of Pharmacy, Alexandria University
• Email: Olaafifi15@gmail.com

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or aromatic compounds.

• A compound is considered Aliphatic when it reacts like an alkane, alkene, alkyne
or one of their derivatives (open chain compounds and their cyclic analogs).
• Aromatic compounds are benzene and compounds that resemble benzene in its
chemical behavior. Although these compounds are highly unsaturated but they
react by substitution rather than addition.
• Aromatic meant then that the compound had a low hydrogen-to-carbon ratio and
that it was “fragrant.” Most of the early aromatic compounds were obtained from
balsams, resins, or essential oils.

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