Page 148 - Pharm.Org.Chem-I 02-06-05-101
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E1 OR E2?
E2 E1
2 steps
Mechanism Single step First order
Reaction rate= k
Kinetics Second order [RX]
Reaction rate= k
[RX][B] Non-
stereospecific
Stereochemistry stereospecific
very weak
Nucleophile Moderate to
strength strong weak
3ry > 2ry > 1ry
Base strength strong
RX 3ry > 2ry > 1ry
Useful links
• https://www.youtube.com/watch?v=235fNIktaPA
• https://www.youtube.com/shorts/lb0DaG_M_so
• https://www.youtube.com/shorts/tNXxBjl81ng
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