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No drug interactions have been reported. However, khellin is reported to inhibit
microsomal cytochrome P450 su benzymes, and may therefore de-crease the serum
concentrations of drugs metabolized via this pathway, such as ciclosporin, warfarin,
estrogens and protease inhibitors.
Nursing mothers:
Owing to the lack of safety data, Ammi visnaga fruits should be taken internally only under
the supervision of health care professionals.
Paediatric use:
Owing to the lack of safely data, Ammi visnaga fruits should be taken internally only under
the supervision of a health-care provider.
Other precautions:
No information available on precautions concerning drug and laboratory test interactions.
Dosage forms:
It is used in the form of dried fruits, infusions, extracts and other galenical preparations.
Store fully dried fruits in well closed containers in a cool and dry place protected from
light.
Posology:
(Unless otherwise indicated)
Average daily dose: Ammi visnaga fruits 0.05-0.15 g.
4- Ammi majus (Fructus Ammi Majoris)
It is the dried ripe fruits of Ammi majus L.
Geographical distribution:
Indigenous to Egypt, and widely distributed in Europe, the Mediterranean region, western
Asia and cultivated in India.
Description
Fruit laterally compressed, oblong, mericarps of the cremocarp separated by a
carpophore.
Cremocarp nearly cylindrical, usually separated into its two mericarps, rarely entire, with
a part of the pedicel attached. Mericarp small, slightly concave on the commissural side,
slightly tapering towards the apex; 2.0-2.5 mm long, 0.75 mm wide, reddish -brownish to
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