Page 143 - Pharmd general phytochemistry I-Final2024_LEUCTERS

Xanthotoxin (Ammoidin). 8-methoxypsoralen, methoxalen:

Source: Ammoidin is mainly obtained from the fruits of Ammi majus and Fragara
xanthoxyloides, Family Umbelliferae, and Ruta graveolens, Family Rutaceae. Ammoidin is

8-methoxyfuranocoumarin (8-methoxypsoralen, 8-MOP).
Some Furanocoumarins of Pharmaceutical Interest

Synthetic

Uses of Psoralen Derivatives:
1. Furanocoumarin derivatives (psoralens) are used as photochemotherapeutic agents

in the treatment of leukoderma (skin depigmentation, vitiligo). Psoralens are used in in
conjunction with exposing the skin to UVB light from lamps or sunlight .
2. They are also used as photochemotherapeutic agents for the treatment of psoriasis &
eczema.

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