Page 3 - Gastrointestinal Bleeding (Xuất huyết tiêu hóa)
P. 3

CHAPTER 20  Gastrointestinal Bleeding  277


                                                                Severe UGI bleeding
                                                                                                                     20

                                                           History and physical examination


                                     Hematochezia,
                   Admission to      syncope, shock,   Type and crossmatch, CBC, chemistry panel,  Stable vital signs and
                      ICU             comorbidities,     liver biochemical tests, coagulation tests.  laboratory values; no
                                   onset of bleeding in       Transfusions as indicated         active bleeding
                                        hospital
                                                          Hemodynamic resuscitation (ongoing)  Admission to standard
                                                                                                 hospital bed

                                                            Gastroenterology consultation

                                       Octreotide (bolus and           High-dose PPI therapy
                                       infusion) if chronic liver      if peptic ulcer suspected
                                       disease suspected or
                                           confirmed
                                                         Hypotension, vomiting red  Stable vital signs with melena or
                                                          blood, or hematochezia;   coffee-ground emesis
                                                             place NG tube


                                            Urgent EGD (after hemodynamic              EGD (or push
                                           stabilization and IV prokinetic agent)  enteroscopy) within 24 hours of
                                            within 6-12 hours of presentation          presentation



                                                              Specific endoscopic treatment (see Fig. 20.2)
                          Fig. 20.1  Algorithm for the initial management of severe UGI bleeding. Some steps may take place simultane-
                          ously or in varying order and in the emergency department, depending on the clinical situation.




              TABLE 20.1  Suspected Source of GI Bleeding as Suggested by a Patient’s History
              Suspected Source of Bleeding       History
              Nasopharynx                        History of nasopharyngeal radiation
                                                 Prior nasopharyngeal malignancy
                                                 Recurrent epistaxis
              Lungs                              Hemoptysis
              Esophageal ulceration              GERD
                                                 Heartburn
                                                 Heavy alcohol use
                                                 Odynophagia
                                                 Pill ingestion
                                                 Traumatic NG tube placement
              Esophageal cancer                  Dysphagia
                                                 History of Barrett esophagus
                                                 Weight loss
              Mallory-Weiss tear                 Alcohol binge
                                                 Vomiting
              Cameron lesions                    Large hiatal hernia
              Esophageal or gastric varices or    Chronic liver disease
                portal hypertensive gastropathy  Cirrhosis
                                                 Morbid obesity
              Gastric angiodysplasia             Aortic stenosis
                                                 Chronic kidney disease
                                                 Systemic sclerosis
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