Page 4 - Gastrointestinal Bleeding (Xuất huyết tiêu hóa)
P. 4

278     PART III  Symptoms, Signs, and Biopsychosocial Issues


           TABLE 20.1  Suspected Source of GI Bleeding as Suggested by a Patient’s History—cont’d
           Suspected Source of Bleeding      History
           Peptic ulcer                      Hp infection
                                             Epigastric discomfort
                                             Frequent aspirin or other NSAID use
                                             History of PUD
           Gastric cancer                    Early satiety
                                             Weight loss
           Primary aortoenteric fistula      Prior severe acute unexplained bleeding and abdominal aortic aneurysm without surgery
           Secondary aortoenteric fistula    Prior surgical repair of an abdominal aortic aneurysm with synthetic graft
           Ampulla of Vater                  Recent endoscopic sphincterotomy
           Bile ducts                        Recent liver biopsy, cholangiography, or TIPS
           Pancreatic ducts                  Pancreatitis
                                             Pseudocyst
                                             Recent pancreatography
           Small intestinal malignancy       Hereditary nonpolyposis colorectal cancer
                                             History of intra-abdominal metastatic cancer
                                             Intermittent SBO
                                             Recurrent unexplained GI bleeding
                                             Weight loss
           Meckel diverticulum               Unexplained GI bleeding in patient ≤40 yr of age
           Small intestinal or colonic ulcerations  IBD
                                             Use of aspirin or other NSAID
           Small intestinal telangiectasias  Frequent nosebleeds
                                             HHT (Osler-Weber-Rendu disease)
           Small intestinal angiodysplasia   Age >60 yr
                                             Chronic GI blood loss
                                             Iron deficiency anemia
           Colonic diverticulosis            Hematochezia without abdominal pain
                                             History of diverticulosis
           Colonic neoplasia                 Change in bowel habits
                                             Chronic bleeding
                                             Personal or family history of colon neoplasia
                                             Weight loss
           Ischemic colitis                  Cardiovascular disease
                                             Hematochezia with or without abdominal pain
           UC                                Bloody diarrhea
                                             Family history of IBD
                                             History of UC
           Crohn disease                     Chronic abdominal discomfort
                                             Family history of IBD
                                             History of Crohn disease
           Anal fissure                      Hematochezia with anal pain
                                             Severe constipation
           Hemorrhoids                       Dripping blood with bowel movements
                                             Hematochezia with otherwise normal bowel movements
           Postpolypectomy ulcer             Recent colonoscopy with polypectomy
                                             Use of anticoagulants or antiplatelet drugs
           Colonic or small intestinal angioectasias  Age >70 yr
                                             Cardiovascular disease
                                             Chronic LGI bleeding/iron deficiency anemia
                                             Recurrent bleeding of variable severity
           Anastomotic ulceration            Prior intestinal surgical anastomosis
           Radiation enteritis or proctitis  History of abdominal radiation therapy

         emesis or fresh bloody emesis that is witnessed do not require   coagulation studies and for typing and crossmatching for packed
         placement of an NG tube for diagnostic purposes but may need   RBCs. The hematocrit or hemoglobin values immediately after
         an NG tube to help clear the gastric blood for better endoscopic   the onset of bleeding may not reflect blood loss accurately,
         visualization and to minimize the risk of aspiration.   because it takes more than 24 to 72 hours for the vascular space
                                                              to equilibrate with extravascular fluid and hemodilution results
                                                                                        5
         Laboratory Studies                                   from IV administration of saline.  A mean corpuscular volume
                                                              (MCV) lower than 80 fL suggests chronic GI blood loss and iron
         Blood from the patient with acute GI bleeding should be sent   deficiency, which can be confirmed by the finding of low blood
         for standard hematology, chemistry, liver biochemical, and   iron, high total iron-binding capacity (TIBC), and low ferritin
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