Page 105 - The Miraculous Machine that Works for an Entire Lifetime: Enzyme
P. 105
Adnan Oktar
sumes the same appearance in the duo-
denum. The state of the food on your
plate is completely different from
how it winds up in the duode-
num. Enzymes break it down, re-
duce its particles in size, elimi-
nate wastes and separate the
rest for the purpose of keeping
your body alive.
g
z
e
v
y
n
D Digestive Enzymes and
e
i
E
t
s
d
n
a
s
e
m
i
t
O
t
a
i
n
o
z
g
r
a
i
n
c
r
T Their Perfect Organization
i
h
e
r
f
e
e
P
When synthesized in the pancre- A computer image of the
enzyme trypsin. The green
atic cells, some enzymes are not yet in an
parts indicate the enzyme's
active state. These become active only after active site.
passing through the intestinal tract. The chemical trypsin, one of the en-
zymes already mentioned, represents a potential danger to the body's
cells. For that reason, it is secreted in an inactive form known as
trypsinogen. The moment trypsinogen makes contact with the intesti-
nal mucosa, the enzyme enterokinase secreted by the mucosa converts
it into its active state. Trypsinogen is also activated by the trypsin that
already exists.
It is most important that these enzymes in pancreatic juice should
not be active before they progress to the intestine, or else trypsin and oth-
er enzymes might digest the pancreas itself. Thus the cells that secrete the
enzymes in question also release a substance known as a trypsin inhibitor,
which prevents trypsin from going into action inside the cells that secrete
it and in the pancreatic duct. Since trypsin can activate other enzymes,
the trypsin inhibitor thus also prevents their activation.
These two enzymes—trypsin and its inhibitor—have no effect
when secreted together. But once they reach the duodenum, they sepa-
103