Page 26 - Imprint-magazine june-Issue
P. 26

Upstream and downstream are processes that covers the entire
     vaccine production journey. Upstream includes cell and media
     selection, high throughput perfusion system, intensified seed train
     and Scale-up. Whereas downstream process deals with harvest and
     clarification, purification and formulation and finally virus analytics.


     Imprint in line with its commitment to more efficient vaccine production
     facilities being built in India, identifies equipment critical in Vaccine
     production. Imprint’s sole aim is to become a source of knowledge that
     provide in-depth information on Vaccine Production Process, and Equip-
     ment. This effort of Imprint will be a guide for companies interested in
     selecting the suitable equipment for their units. And to those interested
     in setting up a new Production Plant.


     Imprint in line with its commitment to more efficient vaccine production
     facilities being built in India, identifies equipment critical in Vaccine
     production. Imprint’s sole aim is to become a source of knowledge that
     provide in-depth information on Vaccine Production Process, and Equip-
     ment. This effort of Imprint will be a guide for companies interested in
     selecting the suitable equipment for their units. And to those interested
     in setting up a new Production Plant.

          Cell Line Vaccine




                                               Manufacturing-2






     Advanced Microbioreactor
     System


          Ambr® 15 Cell Culture Generation 2 from Sartorius





                                            An automated, high throughput microscale bioreactor

                                            system that replicates laboratory scale bioreactor

                                            performance


                                                 he system comprises single-use vessels, an automated workstation and
           Ambr® 15 Cell Culture                 powerful software. Installed in a biological safety cabinet for aseptic
           Generation 2                     Toperation, Ambr® 15 monitors and controls 24 or 48 microbioreactor
                                            cultures in parallel.

                                            As biotherapeutics become more complex, and processes more intensified,
                                            laboratories around the world are facing bigger challenges developing clones,
                                            media and processes.

                                            With key performance enhancements, improved flexibility and significant novel
                                            functions, the Ambr® 15 Generation 2 system helps scientists accelerate their
                                            research.
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