Page 29 - Imprint-magazine june-Issue
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Ambr® 15 microbioreactor vessel



        Mimics the                                 Micro bioreactor vessel
        characteristics of
        lab scale bioreactors to                   The core disposable micro
        enable optimal cell                        bioreactor technology includes
        growth, productivity and                   sensors, stirring impeller, gas
        product quality:                           sparging and sample port.





        •  10 – 15 mL working                       •  Gas sparge tube
             volumes                                •  Sample port with cap
        •  Single-use pH and DO                     •  pH and DO sensor
             sensors                                     spots.
        •  Integrated pitched                       •  Impeller
             blade impeller                         •  Vessels available with
        •  Port for liquid addi-                         temperature compen-
             tions and for sampling                      sation for lower tem-
        •  Vessels available with                        perature applications.
             sparge tube for gassing
             into impeller mixing
             zone, or without for
             headspace gassing



                                          Applications





        Ambr® 15 is the industry standard microbioreactor system, extensively used to
        develop therapies including monoclonal antibodies and recombinant proteins.



                                                         Ambr® 15 is increasingly used to accelerate
                                                         development of newer approaches, such as
                                                         cell and gene based therapies, bispecifics,
                                                         next generation vaccines and antibody drug
                                                         conjugates.


                                                         Ambr® 15 Cell Culture is used as a microscale
                                                         model to eliminate bottlenecks in a range of
                                                         applications such as:


                                                         •  Clone selection
                                                         •  Media, feed and early stage process opti-
                                                            mization
                                                         •  Screening under perfusion mimic condi-
                                                            tions





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