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Pharm D Clinical Pharmacy program 2024-2025 Level 2, Semester 2 Pharmaceutical Dosage Forms II (PT 405)
Method of preparation:
1. Melt the white beeswax and the white soft paraffin, add the olive oil and
heat the mixture up to 75–80 °C.
2. Dissolve the borax in the purified water and heat to 75–80 °C.
3. Add (2) to (1) gradually with trituration while on the bath. Leave for about
5 minutes.
4. Remove from heat with trituration vigorous, one direction trituration, until
cold, viscous white cream is obtained.
Oil phase Aqueous phase
Beeswax Dissolve
Borax in
1a White soft paraffin purified 1b
Olive oil
water
2 Melting at 2Heating atb
a 75-80°C 75-80°C
Add the heated water phase on the melted oil
3 phase with continuous trituration till semi-solid
consistency formation (cream)
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