Page 41 - Practical DF2 Corrected (2)

Pharm D Clinical Pharmacy program 2024-2025 Level 2, Semester 2 Pharmaceutical Dosage Forms II (PT 405)

Method of preparation:

1. In a stainless steel dish →melt beeswax, paraffin wax and cetyl alcohol in a

large dish over a boiling water bath, add mineral oil and heat to 75–80 °C.

2. Dissolve borax in water and heat to 75–80 °C.

3. Add gradually (2) to (1) with vigorous trituration while on the bath, a white

emulsion is produced.

4. Remove from the bath and continue trituration until a homogenous cream is

obtained.

Oil phase Aqueous phase

Beeswax Dissolve
borax in
1 Mineral oil 1b
a Paraffin wax water
Cetyl alcohol

2 Melting at 2Heating atb
a 75-80°C 75-80°C

Add the heated water phase on the melted oil

3 phase with continuous trituration till semi-solid
consistency formation (cream)

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