Page 17 - P4403.59-V63_Numark Pharmacy Magazine May 25
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2 mg/5 ml
 (400 mcg/ml)

 strength     Turn your
 The first non-branded 2 mg/5 ml


 glycopyrronium bromide oral solution   qualification




 An opportunity for adolescents to continue their treatment into adulthood



 For the symptomatic treatment of severe sialorrhoea (chronic   into revenue
 pathological drooling) due to chronic neurological disorders of
 childhood-onset in patients aged 3 years and older.
 1
              with Numark and DigiPharma

 Colonis Glycopyrronium Bromide 2 mg/5 ml Oral Solution
 gives patients the opportunity to continue their stable dose
 into adulthood. 1
               In the ever-evolving world of healthcare,            The future is bright
 •  The 2 mg/5 ml solution is available in 60 ml and 250 ml bottles.  pharmacists are stepping up as Independent   This is where the future lies, and this is where
               Prescribers, ready to make a difference. And
 •  Sugar-free, strawberry flavour – strawberry is the most popular   by 2026 and onwards, every newly qualified   DigiPharma shines—developed by clinicians,
                                                                    not IT specialists, ensuring it meets the real
 flavour with children. 2  pharmacist will already have this skill.  needs of your pharmacy.
 •  A formulation suited for children with swallowing issues. 3  But many of you may find yourselves   Imagine having clear, automated protocols
               underutilising your qualifications, or feel you
                                                                    guiding your consultations. DigiPharma
 •  Licensed for use with nasogastric and/or PEG tubes. 1  are held back by a lack of confidence or   doesn’t just streamline your process; it
               waiting for NHS service commissioning.
 PIP Codes: 128-0841 (60 ml), 128-0833 (250 ml)                     opens up new revenue streams. GPs will
               This is where Numark and DigiPharma                  send more patients your way, and you’ll
               step in…                                             be ready—with the right tools to capture
 Colonis Glycopyrronium Bromide Oral Solution 2 mg/5 ml is now    Exclusive to Numark members, DigiPharma   complete, detailed records while boosting
 available to order via Phoenix  is the revolutionary prescribing recording   your income.
               platform designed to empower pharmacists             Leading the market

 PRESCRIBING INFORMATION   inhaled anaesthetics. May delay absorption of other medication. Concurrent use with slow-  and transform their practice.  We are proud to be partnering with this first
 Please consult the Summary of Product Characteristics (SmPC) before prescribing.   dissolving tablets of digoxin, atenolol or metformin may result in increased serum levels of these   The DigiPharma platform allows for the   to market system from DigiPharma. We
 medicines. Use with parasympathomimetics may antagonise the effect.
 Product name: Glycopyrronium Bromide 2 mg/5 ml Oral Solution  Adverse effects:    know this is the future and we know where
 Composition: Each 5 ml contains 2 mg of glycopyrronium bromide   Serious: Allergic reaction, seizure (worsening), transient bradycardia, angle-closure glaucoma,   creation of an SBAR (Situation, Background,   our profession is going.
 Indications: Symptomatic treatment of severe sialorrhoea (chronic pathological drooling) due to   urinary retention (common), pneumonia (common), pyrexia (common), behavioural   Assessment, Recommendation) for easy GP
 chronic neurological disorders of childhood-onset in patients aged 3 years and older.  changes (very common)  collaboration and enhanced communication.  We’re not just providing you with a tool; we’re
 Dosage and administration: Dosing is based on the weight of the child. Using the graduated   Very common: Dry mouth, constipation, diarrhoea, vomiting, flushing, nasal congestion, reduced
 syringe provided, initiate dosing at 0.02 mg/kg three times daily and titrate in increments of   bronchial secretions. Consult the SmPC for further details and for other adverse reactions.  Based on demand and feedback, this private  offering a nurturing piece that supports a
 0.02 mg/kg every 5-7 days. Adjust dose to achieve optimal symptomatic control with minimal   NHS price: 60 ml: £76.80, 250 ml: £320
 adverse effects. The maximum recommended dosage is 0.1 mg/kg three times daily not   consultation platform bridges the gap,   new era in pharmacy practice and Numark
 exceeding 1.5-3 mg per dose based on weight. Refer to dosing table (Table 1) in Summary of   Legal category: Prescription Only Medicine
 Product Characteristics. Dose should be given one hour before or two hours after meals. For oral   Marketing Authorisation Holder: Colonis Pharma Limited, 25 Bedford Square, Bloomsbury,   capturing what you need efficiently.   and DigiPharma are here to build your
 use and use via nasogastric & PEG feeding tubes.   London, WC1B 3HH, United Kingdom  confidence and support you every step of
 Contraindications: Hypersensitivity to glycopyrronium bromide or excipients; angle-closure   MA number: PL 41344/0071   And this is not just about compliance
 glaucoma; myasthenia gravis; pyloric stenosis; paralytic ileus; prostatic enlargement; urinary   Job number: GB-CPL-066-001  the way.
 retention; severe renal impairment (eGFR < 30 ml/min/1.73 m , including those with end-stage   and communication; it’s also a revenue
 2
 renal disease requiring dialysis); intestinal obstruction; pregnancy & breastfeeding; potassium   Date of preparation: December 2024  generator. Helping to build confidence in   Let’s engage with the future with
 chloride solid oral dose products; other anticholinergic drugs. Contraindicated during pregnancy
 and whilst breastfeeding.  Adverse events should be reported. Reporting forms and information can be found   consultation skills, together, Numark and   confidence, empower your practice and turn
 Warnings and precautions: Not recommended in children under 3 years and should not be used   at: https://yellowcard.mhra.gov.uk/ or search for MHRA Yellow Card in the Google Play or   DigiPharma will be your partners in unlocking  your qualifications into revenue together!
 in children with mild to moderate sialorrhoea or in patients over 65 years. Use with caution in   Apple App Store. Adverse events should also be reported to Colonis Pharma Limited via
 children with compromised blood brain barrier. Reduced dose should be considered for patients   Clinigen E-mail: drugsafety@clinigengroup.com   revenue while maintaining quality of care.
 with renal failure. Use with caution in gastro-oesophageal reflux disease, ulcerative colitis,   Fax number: +44 (0) 1932 824284
 pre-existing constipation, acute myocardial infarction, hypertension, conditions characterised   Unlock an exclusive 10%
 by tachycardia (including hyperthyroidism, cardiac insufficiency, cardiac surgery), coronary   By having the competence and confidence,
 artery disease, cardiac arrhythmias, patients receiving inhalation anaesthesia. Diarrhoea may   Abbreviation  you can deliver more private services and   discount today and visit
 be an early symptom of incomplete intestinal obstruction, especially in patients with ileostomy   PEG, percutaneous endoscopic gastronomy.
 or colostomy, and treatment with this drug would be inappropriate and possibly harmful. As   even differentiate yourself in the market   numarknet.com/digi-pharma
 glycopyrronium bromide inhibits sweating, patients with increased temperature should be   References
 observed closely. In high environmental temperature, heat prostration can occur. Avoid repeated   1.  Colonis Pharma Ltd. Glycopyrronium Bromide 2 mg/5 ml Oral Solution Summary of Product   by providing specialised services that other
 or large doses in patients with uraemia. Patients with fructose intolerance should not take this   Characteristics. Available from: https://www.medicines.org.uk/emc/.
 medicine due to presence of sorbitol. The product contains sodium propyl parahydroxybenzoate   2.  Generation R. What flavour would children choose for their medicines? Available from: https://  pharmacies may not offer. This will attract
 (E217) and sodium methyl parahydroxybenzoate (E219) which may cause allergic reactions   generationr.org.uk/what-flavour-would-children-choose-for-their-medicines/
 [Accessed January 2025].
 (possibly delayed). Treatment should be evaluated in the event of constipation, overheating,   3.  Batchelor HK and Mariott JF. Formulations for children; problems and solutions. Br J Pharmacol.   a broader customer base and tap into niche
 urinary retention, pneumonia, allergic reaction, pyrexia, very hot weather, changes in behaviour.   2015;79(3):405–418.
 Safety data beyond 24 weeks are not available. Treatment should be kept as short as possible.   markets requiring specific clinical expertise.
 May produce drowsiness or blurred vision, thus patients should not operate machinery.  © Colonis Pharma Limited 2025
 Drug interactions: Combinations with drugs with antimuscarinic effects (e.g. amantadine,   Registered in England & Wales No. 05486832. For more information please view our Privacy
 tricyclic antidepressants, antihistamines, clozapine; disopyramide; MAOIs, nefopam; memantine,   Policy. VAT Registration No. 862418028. Registered office: Colonis Pharma Ltd, 25 Bedford Square,
 phenothiazines) may add to adverse effects and can also lead to confusion in the elderly. Use   Bloomsbury, London, WC1B 3HH.
 with corticosteroids may result in increased intraocular pressure. There are specific interactions
 with domperidone, metoclopramide, levodopa, haloperidol; nitrates; topiramate, zonisamide;   January 2025 | GB-CPL-066-002
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         P4403.59-V63_Numark Pharmacy Magazine May 25 -.indd   17                                                14/04/2025   12:45:38
         P4403.59-V63_Numark Pharmacy Magazine May 25 -.indd   17
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