Page 8 - P4304.1-V93_PS-Magazine-January 2024 -
P. 8

REVOLUTIONISING THE WAY, YOU                                                                                     Helping your patients live

                                  OPERATE IN 2024 WITH                                                                              in harmony with creatures                                                         Live like you

                 GOLDEN TOTE                                                                                                        great and small                                                           Ryaltris is indicated in adults and


                                                                                                                                                                                                              adolescents 12 years of age and older
                                                                                                                                                                                                              for the treatment of moderate to
                                                                                                                                                                                                              severe nasal symptoms associated
                                                                                                                                                                                                              with allergic rhinitis (AR). 1




              As we step into the new year, the opportunities        This newfound efficiency saves you valuable
              for your dispensary business are as fresh             time, which can be better spent on embracing
              as the beginning of January. We know that             new business opportunities. Say goodbye
              dispensaries are facing many challenges from          to time-consuming tasks like invoice
              staff retention and recruitment through to            verification, order placement, and frequent
              more items and less headroom. Therefore, try          stock management chores.
              something different for the new year to adapt         Golden tote is also vital for performing
              to these challenges such as Golden tote.              accuracy checks, as mentioned with the
              We’ve showcased the advantages of Golden              increased workload, and staffing challenges
              tote through-out the last year at our Live            mistakes are more likely to be made, however
              PSUK live study days and the response has             Golden Tote steps up to make sure you have
              been nothing short of brilliant!                      piece of mind.
              Golden Tote offers a transformative solution          Golden Tote is your partner in liberating you                   Ryaltris  combination intranasal spray can bring symptom
                                                                                                                                               ®
              that can usher in a promising era for your            from the dispensary bench, allowing you to
              dispensary, revolutionising the way you               focus on providing care to your community,                      relief within 10-15 minutes* from allergic rhinitis triggered by
              operate in 2024 .                                     both now and well into the future. Embrace                      perennial factors such as animal dander and dust mites.                        1-4
                                                                    the new year, embrace the new possibilities,                    *Findings from one environmental exposure chamber study and two large randomised controlled trials. 2-4
              Our  dispensing solution is your key to                                                                               Ryaltris is generally well tolerated; the most commonly-reported adverse reactions are dysgeusia,
              unlocking the full potential of your dispensary.      and embrace the future of your dispensary                       epistaxis and nasal discomfort. 1,2,5
              It’s not just a digital system; it’s a catalyst for   business with Golden Tote.                                                                                                                                     Scan to visit
              growth and flexibility. This innovative system        The interest in Golden Tote from our members                    Find out more at www.ryaltris.co.uk                                                     www.ryaltris.co.uk
              has demonstrated its ability to enhance               has been nothing short of remarkable. Many
              safety, streamline operations, and elevate            have expressed a keen desire to witness a                       Ryaltris Prescribing Information                      during periods of stress or elective surgery. The replacement of a systemic corticosteroid
              precision, all within an easily manageable            live demonstration of our solution aboard                       Ryaltris  (mometasone  furoate  and  olopatadine  hydrochloride)  Please  refer  to  the  with a topical corticosteroid can be accompanied by signs of adrenal insufficiency, and
                                                                                                                                    Summary of Product Characteristics (SmPC) before prescribing. One delivered dose
                                                                                                                                                                                          some patients may experience symptoms of withdrawal. Patients previously treated for
              package that seamlessly integrates into your          our fully installed vans. Don’t miss out on this                contains mometasone furoate monohydrate equivalent to 25 microgram mometasone   prolonged periods with systemic corticosteroids and transferred to topical corticosteroids
                                                                                                                                                                                          should  be  carefully  monitored  for  acute  adrenal  insufficiency  in  response  to  stress.
                                                                                                                                    furoate  and  olopatadine  hydrochloride  equivalent  to  600  micrograms  olopatadine.
              dispensary processes.                                 opportunity; you can still schedule visits to                   Indication:  treatment  of  moderate  to  severe  nasal  symptoms  associated  with  allergic   In  those  patients  who  have  asthma  or  other  clinical  conditions  requiring  long  term
                                                                                                                                    rhinitis  in  adults  and  adolescents  12  years  of  age  and  older  Posology  and  method  of  systemic corticosteroid treatment, too rapid a decrease in systemic corticosteroids may
              With Golden Tote, we bring you the                    your practice and let us bring Golden Tote to                   administration:  The  usual  recommended  dose  is  two  actuations  in  each  nostril  twice   cause a severe exacerbation of their symptoms. Somnolence: in isolated cases dizziness,
                                                                                                                                    daily  (morning  and  evening).  Children  below  12  years:  Ryaltris  is  not  recommended.
                                                                                                                                                                                          lethargy,  fatigue  and  somnolence  may  occur  when  using  Ryaltris.  In  these  cases,  the
                                                                                                                                    Elderly: No dose adjustment required. Renal and hepatic impairment: there are no data
                                                                                                                                                                                          ability to drive and use machines may be impaired. Alcohol and other CNS depressants
              opportunity to embrace automation, with the           you, and together, we’ll set the stage for your                 in patients with renal and hepatic impairment, however no dose adjustment is expected   may enhance this effect. Antihistamine effects: concomitant use of other antihistaminic
                                                                                                                                    to be required. Contraindications: Hypersensitivity to the active substances or to any of
                                                                                                                                                                                          drugs  administered  may  increase  the  risk  of  antihistamine  adverse  effects.  Paediatric
              integration of barcode scanning technology            dispensary’s success in the months ahead.                       the excipients. Ryaltris should not be used in the presence of untreated localised infection   population: It is recommended that the height of children receiving prolonged treatment
                                                                                                                                                                                          with nasal corticosteroids is regularly monitored. If growth is slowed, therapy should be
                                                                                                                                    involving the nasal mucosa, such as herpes simplex. Patients who have experienced recent
              into our “pick to prescription” application           Visit the PSUK website for more details or                      nasal surgery or trauma should not use a nasal corticosteroid until healing has occurred.   reviewed with the aim of reducing the dose of nasal corticosteroid if possible, to the lowest
                                                                                                                                    Precautions: Local nasal effects: nasal ulceration and nasal septal perforation have been
                                                                                                                                                                                          dose at which effective control of symptoms is maintained. Excipients: Ryaltris contains
              simplifies prescription assembly directly from        get in touch with your dedicated Dispensing                     reported in patients following intranasal antihistamines. Nasal septal perforation has been   0.02  mg  benzalkonium  chloride  in  each  actuation.  Benzalkonium  chloride  may  cause
                                                                                                                                                                                          irritation or swelling inside the nose, especially if used for a long time. Adverse reactions:
                                                                                                                                    reported following intranasal corticosteroids. Patients using Ryaltris over several months
              the PHOENIX tote, eliminating the need for            Doctor Account Manager to kickstart the                         or  longer  should  be  examined  periodically  for  possible  changes  in  the  nasal  mucosa.   Common  (≥1/100  to  <1/10):  dysgeusia  (unpleasant  taste),  epistaxis,  nasal  discomfort.
                                                                                                                                                                                          Uncommon  (≥1/1,000  to  <1/100):  dizziness,  headaches,  somnolence,  nasal  dryness,  dry
                                                                                                                                    Ryaltris is not recommended in cases of nasal septum perforation. In clinical studies with
              double-handling stock.                                year with the best tools at your disposal.                      mometasone furoate administered intranasally, the development of localised infections   mouth, abdominal pain, nausea, fatigue. Rare (≥1/10,000 to <1/1000) bacterial vaginosis,
                                                                                                                                                                                          anxiety, depression, insomnia, lethargy, migraine, blurred vision, dry eye, eye discomfort,
                                                                                                                                    of the nose and pharynx with Candida albicans has occurred; may require treatment and
                                                                                                                                    discontinuation of Ryaltris. Patients using Ryaltris over several months or longer should be   ear  pain,  nasal  inflammation,  nasal  mucosal  disorder,  oropharyngeal  pain,  sneezing,
                                                                                                                                    examined periodically for evidence of Candida infection or other signs of adverse effects   throat  irritation,  constipation,  sore  tongue,  laceration.  Incidence  not  known  (reported
                                                                                                                                    on  the  nasal  mucosa.  Visual  disturbances  may  be  reported  with  systemic  and  topical   from use of corticosteroids): pharyngitis, upper respiratory tract infection, hypersensitivity
                                                                                                                                    corticosteroid use. Symptoms such as blurred vision or other visual disturbances should   including anaphylactic reactions, angioedema, bronchospasm, and dyspnoea, cataracts,
                                                                                                                                    be  considered  for  ophthalmologist  referral  for  evaluation  of  possible  causes  including   glaucoma,  increased  intraocular  pressure,  nasal  septum  perforation.  Marketing
                                                                                                                                    cataract,  glaucoma  or  rare  diseases  such  as  central  serous  chorioretinopathy  (CSCR).   authorisation number: PL 25258/0331 Marketing Authorisation Holder and distributer:
                                                                                                                                    Hypersensitivity  Reactions  including  instances  of  wheezing,  may  occur.  Discontinue   Glenmark  Pharmaceuticals  Europe  Limited,  Laxmi  House,  2B  Draycott  Avenue
                                                                                                                                    Ryaltris  if  such  reactions  occur.  Immunosuppression:  Chickenpox  and  measles,  for   Kenton,  Middlesex,  HA3  0BU.  United  Kingdom  Legal  classification:  POM  Cost:  £13.32.
                                                                                                                                    example, can have a more serious or even fatal course in susceptible patients and those   1  bottle  with  29  g  suspension  (240  actuations)  Date  of  preparation:  June  2021.  Job
                                                                                                                                    using  corticosteroids.  In  children  or  adults  who  have  not  had  these  diseases  or  been   number: PP-UK-RYAL-0001
                                                                                                                                    properly immunized, particular care should be taken to avoid exposure. Corticosteroids
                                                                                                                                    should  be  used  with  caution,  if  at  all,  in  patients  with  active  or  quiescent  tuberculous   Adverse events should be reported. Reporting forms and information
                                                                                                                                    infections of the respiratory tract, untreated local or systemic fungal or bacterial infections,   can be found at https://yellowcard.mhra.gov.uk. Adverse events should
                                                                                                                                    systemic viral or parasitic infections, or ocular herpes simplex because of the potential   also be reported to Glenmark Pharmaceuticals Europe Ltd
                                                                                                                                    for worsening of these infections. Systemic Effects of Corticosteroids: potential systemic
                                                                                                                                    effects  may  include  Cushing’s  syndrome,  Cushingoid  features,  adrenal  suppression,   medical_information@glenmarkpharma.com or call 0800 458 0383
                                                                                                                                    growth retardation in children and adolescents, cataract, glaucoma and more rarely, a
                                                                                                                                    range of psychological or behavioural effects including psychomotor hyperactivity, sleep   References: 1. Ryaltris Summary of Product Characteristics. 2. Gross GN, et al. Ann
                                                                                                                                    disorders,  anxiety,  depression  or  aggression  (particularly  in  children).  When  intranasal   Allergy Asthma Immunol 2019;122:630–638. 3. Hampel FC, et al. Allergy Asthma Proc
                                                                                                                                    steroids  are  used  at  higher  than  recommended  dosages  or  in  susceptible  individuals   2019;40(4):261–272. 4. Patel P, et al. Ann Allergy Asthma Immunol 2019;122(2):160–166.
                                                                                                                                    at  recommended  dosages,  systemic  corticosteroid  effects  such  as  hypercorticism  and   5. Segall N, et al. Allergy Asthma Proc 2019;40:301-310.
                                                                                                                                    adrenal  suppression  may  appear.  If  such  changes  occur,  the  dosage  of  Ryaltris  should
                                                                                                                                    be  discontinued  slowly,  consistent  with  accepted  procedures  for  discontinuing  oral   Ryaltris  is a registered trademark of Glenmark Speciality S.A.
                                                                                                                                                                                               ®
                                                                                                                                    corticosteroid  therapy.  The  concomitant  use  of  intranasal  corticosteroids  with  other   © 2023 Glenmark Pharmaceuticals Europe Ltd.
                                                                                                                                    inhaled corticosteroids could increase the risk of signs or symptoms of hypercorticism
                                                                                                                                    and/or suppression of the HPA axis. If there is evidence for higher than recommended   All rights reserved.
                                                                                                                                    doses  being  used,  then  additional  systemic  corticosteroid  cover  should  be  considered   Date of preparation: October 2023  PP-UK-RYAL-0338 V1
         P4304.1-V93_PS-Magazine-January 2024.indd   8
         P4304.1-V93_PS-Magazine-January 2024.indd   8                                                           14/12/2023   10:11:04
                                                                                                                 14/12/2023   10:11:04
                                                                                                                                                                                                                                           30/10/2023   09:34
                                                                                                                               020006_AW_Ryaltris_PSUK_210x297mm.indd   1
                                                                                                                               020006_AW_Ryaltris_PSUK_210x297mm.indd   1                                                                  30/10/2023   09:34
   3   4   5   6   7   8   9   10   11   12   13