Page 7 - PBA Medicine list - edition 5_SW_Neat

By Michelle

Generic Name: Erythromycin

Brand names: EES, E-mycin, Eryc

Side effects/precautions:

Allergic reaction side effects, dizziness, muscle pain, weakness

Precautions: if used for more than 3 weeks check renal function and red blood count.

Interactions:

Erythromycin (should not coadmin); CYP3A4/ 3A5 inhibitors, strong 3A4 inducers eg rifampicin;
neuromuscular blockers. Antagonism has been demonstrated between clindamycin and erythromycin
in vitro. Because of possible clinical significance, these two drugs should not be administered
concurrently.

Reasons for interactions:

Increased risk of myopathy and hepatic function.

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