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Clinical pharmacy PharmD program Third level Phytochemistry-1 (PG-504)

•Spectroscopic methods such as HPLC, GC-MS, ..etc

Medicinal Importance of Glycosides

e.g:

1. Cardiac drugs, cardiac glycosides, such as glycosides of digitalis, strophanthus, squill.

2. Laxatives; such as the anthraquinone glycosides of senna, aloes, rhubarb, cascara and
frangula.

3. Counter irritants; such as the thioglycosides, and allylisothiocyanate, a hydrolytic product
of the glycoside sinigrin.

4. Analgesics; such as methyl salicylate, a hydrolytic product of the glycoside gaultherin.

5. Renal disinfectants; such as the glycosides arbutin.

6. Anti-rheumatics such as the glycoside salicin.

7. Reduction of capillary fragility; e.g. rutin, hisperidin.

8. Anti-inflammatory such as the glycoside glycyrrhizin which has also demulcent,
expectorant.

ALCOHOL Glycosides

Salicin

Is classified both as an alcoholic, as it contains free primary alcoholic group as well as
a phenolic glycoside as its aglycone is phenolic.

Source: Salix (White Willow) bark.

Uses: treatment of fever and rheumatism due to its

analgesic - antipyretic, anti - inflammatory and antirheumatic properties closely resembles
that of salicylic acid.

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