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Clinical pharmacy PharmD program                     Third level                          Phytochemistry-1 (PG-504)




              Structure Determination of Terpenes and the Isoprene Rule

                 •  The molecule is made up of the union of two or more isoprene units

                 •  The units are usually united in a “head to tail manner”



















              The union of two or more isoprene units gives different classes of compounds as in the following
              table:


                                                No. of  units     No. of  C        Formula

                                               isoprene          carbon
                                Hemite                                               5   8
                                                      1                5             C  H
                                Monote                 2               10            C  H
                                rpenes

                                                                                     10  16
                                 rpenes                3               15            C  H
                                Sesquit                                              15  24
                                erpenes                4               20            C 20 H 32
                                Diterpe

                                   nes

                                Sisterte               5               25            C  H
                                                                                     25  40
                                 rpenes
                                Triterp                6               30            C 30 H 48


                                   enes                n              5n                 n
                                Polyter
                                                                                  (C 5 H 8 )
                                  penes






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