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Clinical pharmacy PharmD program Third level Phytochemistry-1 (PG-504)

Lactose intolerance:

• Lactose transmits through the small intestine undigested due to insufficient

lactase activity on the intestinal surface.

• Undigested lactose transits to the large intestine where unadapted colonic

bacteria attempts to ferment (metabolize) the lactose.

• Lactose fermentation results in large quantities of gas, causing flatulence,

distention and acute diarrhea.

Uses of Lactose

 Lactose is used as nutrient in infant foods, since it is less sweet than sucrose

and more easily digested.

 Inert diluent for other drugs in tablets and powders.

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