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Clinical pharmacy PharmD program Third level Phytochemistry-1 (PG-504)
1) Sucrose= sugar, saccharose, cane-sugar or beat sugar
• It is also known as sugar, saccharose, cane-sugar or beat sugar.
• Having α 1 ➔ β 2 glycosidic linkage
• It occurs in many members of the plant kingdoms. Commercial sources are:
o Sugar cane (Saccharum officinarum, family Geraminae = Poaceae).
o Sugar beet (Beta vulgaris, family cruciferae).
• Plants store starch in roots, tubers, and leafy parts, mainly during photosynthetic
activity; some plants, such as sugar beets and sugar cane, also store sucrose.
Properties:
• Anhydrous crystalline solid, very soluble in water.
• When heated over its melting point (to 210 C), it undergoes partial
o
decomposition to form caramel (light brown amorphous substance that used to
color sweets).
o
• It is dextrorotatory (specific rotation = + 66.5 ).
Chemically, it is: -D-Glucopyranosyl--D-fructofuranoside. Or
-D-Fructofuranosyl--D-glucopyransoide.
Preparation: (from sugar cane, Saccharum officinarum)
• The juice of sugar cane (18% sucrose) is made very slightly alkaline by lime,
heated; the formed scum and the precipitated impurities are separated.
• The clear juice is evaporated under vacuum and the crystallized raw sugar is
separated. The left liquor is known as molasses.
• The raw sugar is then refined by washing in centrifugal then dissolved and
filtered.
• The filtered solution is decolorized by passage through columns filled with
activated animal charcoal.
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