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PharmD clinical pharmacy program Level 3, Semester 2 Biopharmaceutics & Pharmacokinetics (PT608(

Oral absorption

Monitoring drug in blood/plasma

Plasma concentration-time curves show the drug absorption and elimination rate processes

Absorption phase:

- Absorption rate more than elimination rate.
- Elimination occurs whenever a drug is present in the plasma, even though
absorption predominates.

- At the peak plasma concentration, the absorption rate just equals the elimination rate.

 Postabsorption phase: Elimination rate more than absorption rate

Elimination phase

- No significant absorption occurs (only the elimination process).

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