Page 53 - Interactive Theoritical Notes of Bioharmaceutics and pharamcokinetics.docx compressed

PharmD clinical pharmacy program Level 3, Semester 2 Biopharmaceutics & Pharmacokinetics (PT608(

Upon integration ➔
[[[[

(Xa)t=0: Mass or amount of absorbable drug at the site of administration at time

t=0 (for extravascular administration of a drug, (Xa)t=0 equals FX0)

F: Fraction or percentage of the administered dose that is available to reach the

general circulation

X0: Administered dose of a drug

Ka: Absorption rate constant

K: Elimination rate constant

When written in concentration (Cp) terms➔
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