Page 72 - DUOKOPT BIBLIOBOOK

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KEY MESSAGES

X A 3-month prospective study with 60 patients comparing 24H efficacy between DTFC/
BTFC.

X DTFC is more efficient on 24-hour IOP than BTFC.

STRENGTHS

X Both fixed combinations significantly reduce 24-hour IOP in POAG. DTFC provided signi-
cantly better 24-hour efficacy than BTFC.

X This is the first study comparing the 24-h efficacy of these two fixed combinations.

WEAKNESSES

X The approach, solely based on pharmacologic efficacy, is not ideal, as it does not take
into account other important clinical benefits such as enhanced adherence, improved
convenience, and reduced cost to patients

MARKETING CLAIM

X DTFC is more efficient on 24-hour IOP than Brimonidine-Timolol fixed combination.

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