Page 173 - Critical Maternity & Newborn Health Nursing
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•  Eclampsia                               after 20 weeks  or in early

                                                               postpartum

                                                            •  Development of convulsions  or
                    •  Chronic             hypertensive
                                                               coma in preeclamptic patient
                        disorders:-

                        o  Chronic hypertension
                                                            •  Hypertension and / or proteinuria
                        o  Superimposed              pre-
                                                               in pregnant patient with chronic
                           eclampsia / eclampsia
                                                               hypertension


                                                            •  Development of pre-eclampsia or
                                                               eclampsia in patient with chronic


                                                               hypertension


                   Risk factors: [Predisposing factors]


                       1.  Primigravida under 19 years.                      6. Diabetes.

                       2.  Low socioeconomic status.                         7. Multiple gestations.

                       3.  History of sever pre-eclampsia.                   8.              Chronic

                          hypertension.

                       4.  Familial history.                                      9. Hydatidiform mole.


                       5.  Rh incompatibility.


                   Pathophysiological changes result from preeclampsia: -


                       1.  Uteroplacental insufficiency: -

                          This related to spiral arteriole lesions and  a deficiency of

                          prostacyclin, [vasodilator] this lead to constriction of umbilical

                          vessels, which leads to decrease fetal blood flow.

                       2.  Kidney damage: - (Occurs in 70 % of cases)


                          •  Glomerular endothelial damage.                         -Fibrin
                              deposition.


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