Page 176 - Critical Maternity & Newborn Health Nursing

• Hyperbilirubinemia [Jaundice] may develop due to hemolysis of

RBCs.

• Endothelial damage and fibrin deposition cause impaired liver

function which result in increased hemorrhagic necrosis, which,

characterized by right upper quadrant tenderness or epigastric

pain nausea & vomiting. Also it leads to elevation of liver

enzymes.

3. Low platelets count: -

This due to systemic capillary endothelial cell damage, which

activates platelet adherence and fibrin deposition.

HELLP syndrome signs: -

• Epigastric pain. Nausea & vomiting.

• Headache. Malaise.

• Jaundice. Hematuria.

Maternal effects:

Maternal mortality 10% to 24%. This is due to pulmonary edema, renal or

hepatic failure, myocardial infarction, or cerebral Hemorrhage.

Fetal effects:

Perinatal mortality 35% to 65%. Due to placental insufficiency,

intrauterine growth retardation, Prematurity and abruptio placenta

Signs & symptoms: -

1. Hypertension: -

• The diastolic Bl. pressure is 150 mmHg or greater on any one

occasion.

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