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םיליעי םיילקיפוט םירישכת                                                                PSO & SKIN CONTROL
                                                                                                                                          אפרמ יחמצ
                                                    BIO BALANCE
                                                                                                                                רועה עדמ תורשב
                                                     .
                                   .                     	           ,                                     CONTROL BOTANIPLEX™          	        .

                                                            
      BOTANIPLEX®
                           
           ,
    
                                                   .                  ,
                                                                                                     ,
                                                            .                                                                    
      ,
                                                                                                          ,  	 	        	  :                           .
                                                                                               PSO CONTROL
                                                          BARRIER
                                                                                                                                    EXFOLIATING
                                                                                            RICH BODY CREAM                       CLEANSING BAR
                                              PROTECTING SERUM
                                 	                                                                         .                   ,  	 	            ,     ,
         ,
   	    :
                           	   ,        	                         .

                       B5 
  	       ,            .                                          
            ,                                   .
                                        ,             
    
                  	                                                      	           (BOTANIPLEX™)

                                                ,
                             *                                                              :
                                                         .(96.5%)
                                          .                                                          FDA        ,
              .     24                        •                    ,                          ,        ,                        :
                                          •                                                                                             ,               .
                                          
     FDA
                        .

                                                       MULTI CARE
                                                      ,
                                                     MOISTURIZER
                                           .

            , 
        	   :                        .(Transepidermal Water Loss) TEWL                                             PSO CONTROL RICH BODY CREAM
                                                                                                                                                          ANTI
                                                                                                                    ANTI
                                                                                                                                 ANTI
                                                                                                                                           PREBIOTIC
              ,          ,B5 
  	       ,                                                           6                    58%          .
                                              .       ,(97.8%)     	                                           INFLAMMATORY   ALLERGIC                    ITCH
                                                                                                                                         6           83%

                                             ,
                             *
                         .                                      ,SLS ,
                                             ,
         93%                                 •   .                                                                PSO Body Cream - Clinical Study
                   25%                       •
              ,     28                         •   .(                          )               0%   Week 2   Week 4    Week 6       0%   Week 2   Week 4   Week 6
                                                                                              -20%                                -20%
                                                                                                     -15%
                                                                                              -40%            -45%               % of change (itch level)  -40%  -29%
                                                                                                                                  -60%
                                                                                              -60%

             	  	    (Corneometer)   	                 28              ,      20        *   % of change in PASI  -80%  -58%       -80%            -54%


                                      	           50                       (Cutometer)
                                                                                             -100%                                -100%                     -83%


                                                                                               P<O.01 week 2. week 4. week 6 vs. baseline. N•20  P<0.01 week 2. week 4, week 6 vs. baseline. N•11
                                                 GENTLE RADIANCE                               PASI = Psoriasis Area Severity lndex  VAS (Visual Analogue Scale)
                                                FACIAL CLEANSER

                                                   :
                                                   
   	    ,




                  ,CALM


                                                                                                        6
                              AC - CLEAR SPOT TREATMENT
                                                                                                                                                        CALM
                        CALM INTENSE MOISTURE CREAM                    חכומ                                                                           CLEAR
                                                                       חכומ
                           SPOT TREATMENT
                          .               3 -                  1



                                           .
                                .SCORAD      "                                                                           
           ,
                                                                                                                                            	        .
                                                                      תירקחמ
                                                                     תירקחמ                                                   ,CLEAR BOTANIPLEX™
                                                                                                                                             - CALM BOTANIPLEX™
                                                   .        2                                                       .
                                                                                                                                       ,
                                                                                                                                .
                       .    	                10
                                                                                                             CALM
                                                                  46%     
                  REPAIR HAND CREAM
                              .                3
                                                                                                 .
                                                                                                 ANTI-BLEMISH                          PURIFYING GEL
           100%                                                                                   FACE CREAM                         FACE CLEANSER
                     Week 1                Week 2                Week 3 88.3                                                                             '
           90%
             0%
                                                                                                                                        
            ,
           80%                                                                                :
                       -3%                           73.3
                                                                                                                                    :
            -10%                                                                              
       ,                            E 
  	   ,
            70%

         Overall Improvment (%) % Change in SCORAD  -20%  38.3  53.3  -26%  38.32  45    GENTLE SOOTHING WASH
           60%
                                                                                                       CALM BABY
                                                                                                                                        CALM GENTLE
           50%
                                                                                                                                     SOOTHING WASH

                                                                                                     PURIFYING
                                                                                                                                               CLEAR
           40%
                                                                                                 :
           -30%
                                                                                                                                    SPOT TREATMENT
                                                                                               CLEANSING BAR
                                                                                                                                    :
           30%




           20%
           -40%                                                                                          	                                            	   '
            10%     6.66  6.66  6.66                              -46%                       :                                                :
                                                                                                          ,                                  12
            0%
           -50%                                                                                                                     :
                                                                                             INSTANST RELIEF GEL
           -10%  p<0.01 Week 2, Week 3 vs. baseline, N = 30                                                	          '                CALM INTENSE
                                                                                                                                              
       ,2%
                          2
                     1
               0 SCORAD at baseline = 42±12  4  5  6    7     8     9    10                                                         MOISTURE CREAM
                                3
                SCORAD (Scoring of Atopic Dermatitis)
                                     Duration (Day #)
                                                                                                 :
                 Control     Kamedis spot treatment
                                                                                                                                               CLEAR
                                                                                                      Hydroxyphenyl)                 :
                                                                                                                                        PIMPLE PATCH
                                                                                                   Propamidobenzoic
                                                                                                               ,(Acid

                                                                                                                                 ,               .
                                                                                                                                      .
                                                                                                                                    :
                                                                                                                            .
                                                                                                                                                ULTRA
                                                                                                                                      .
                                                                                                                                      HYDRATION GEL
                                                                                                         DRY SKIN                                          '
                                                                                                        FOOT GEL
                                                                                                                                                     אלל
                                                                                                                     '                 		                     אלל
                                                                                                                                          י”ע ץלמומ

                                                                                                                                      :

                                                                                                                                                  םייתוכאלמ םיעבצ
                    10                                                                           :                                 
   	    ,

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