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םיליעי םיילקיפוט םירישכת          PSO & SKIN CONTROL
                                                      אפרמ יחמצ
 BIO BALANCE
                                            רועה עדמ תורשב
                                        .

                    .                     	           ,                          CONTROL BOTANIPLEX™          	        .
                 
      BOTANIPLEX®
       
           ,
    
                                     .                  ,
                 ,
 .                                             
      ,
                                                EXFOLIATING
                      ,  	 	        	  :                           .
 BARRIER
           PSO CONTROL
                                          RICH BODY CREAM  CLEANSING BAR
 PROTECTING SERUM
             	                                            .                   ,  	 	            ,     ,
  ,
   	    :
   	   ,        	                         .

 B5 
  	       ,            .                           
            ,                      .
                    ,             
    
                  	                                   	           (BOTANIPLEX™)

  ,
 *             :
             .(96.5%)
 .                                     FDA        ,
 .     24                        •                 ,       ,        ,           :
                    •                               ,               .
         
     FDA
 .

 MULTI CARE
                              ,
 MOISTURIZER
                       .

  , 
        	   :                        .(Transepidermal Water Loss) TEWL                                      PSO CONTROL RICH BODY CREAM
                                             ANTI
                                                                      ANTI
                                ANTI
                                                       PREBIOTIC
        ,          ,B5 
  	       ,                                                6                    58%          .
              .       ,(97.8%)     	         INFLAMMATORY  ALLERGIC   ITCH
                                                     6           83%

  ,
 *
 .                                      ,SLS ,
  ,
   93%                                 •   .                            PSO Body Cream - Clinical Study
         25%                       •
        ,     28                         •   .(                          )  0%  Week 2  Week 4  Week 6  0%  Week 2  Week 4  Week 6
                                         -20%  -20%
                                -15%
          -40%            -45%               % of change (itch level)  -40%  -29%
                                              -60%
          -60%

   	  	    (Corneometer)   	                 28              ,      20        *  % of change in PASI  -80%  -58%  -80%  -54%


                  	           50                       (Cutometer)
         -100%                                -100%                     -83%


           P<O.01 week 2. week 4. week 6 vs. baseline. N•20  P<0.01 week 2. week 4, week 6 vs. baseline. N•11
  GENTLE RADIANCE  PASI = Psoriasis Area Severity lndex  VAS (Visual Analogue Scale)
 FACIAL CLEANSER

  :
 
   	    ,




        ,CALM


                    6
                                                                    CALM
 AC - CLEAR SPOT TREATMENT
 CALM INTENSE MOISTURE CREAM        חכומ                          CLEAR
 חכומ
 .               3 -                1
  SPOT TREATMENT



 .
 .SCORAD      "                      
           ,
                                                        	        .
 תירקחמ
                                      תירקחמ            ,CLEAR BOTANIPLEX™
                                                         - CALM BOTANIPLEX™
 .        2                     .
                                                   ,
                                            .
 .    	                10
                         CALM
 46%     
     REPAIR HAND CREAM
 .                3
              .
             ANTI-BLEMISH                          PURIFYING GEL
 100%         FACE CREAM                         FACE CLEANSER
 Week 1  Week 2  Week 3 88.3                                               '
 90%
 0%
                                                    
            ,
 80%      :
 -3%  73.3                                      :
 -10%
 70%      
       ,                            E 
  	   ,

 Overall Improvment (%) % Change in SCORAD  40%  38.3  53.3  -26%  38.32  45  GENTLE SOOTHING WASH
 60%
                   CALM BABY
                                                    CALM GENTLE
 -20%
 50%
                                                 SOOTHING WASH

                 PURIFYING
                                                           CLEAR
             :
 -30%
           CLEANSING BAR
                                                SPOT TREATMENT
                                                 :

 30%



 20%
 -40%                	                                            	   '
 10%  6.66  6.66  6.66  -46%  :                                 :
                      ,                                  12
 0%
 -50%                                           :
         INSTANST RELIEF GEL
 -10%  p<0.01 Week 2, Week 3 vs. baseline, N = 30               	          '   CALM INTENSE
                                                          
       ,2%
 2
 3
 1
 0 SCORAD at baseline = 42±12  4  5  6  7  8  9  10                    MOISTURE CREAM
 SCORAD (Scoring of Atopic Dermatitis)
 Duration (Day #)
             :
 Control  Kamedis spot treatment
                                                           CLEAR
                  Hydroxyphenyl)                 :
                                                    PIMPLE PATCH
               Propamidobenzoic
                           ,(Acid

                                             ,               .
                                                  .
                                                :
                                         .
                                                            ULTRA
                                                  .
                                                  HYDRATION GEL
                     DRY SKIN                                          '
                    FOOT GEL
                                                                 אלל
                                 '                 		                     אלל
                                                      י”ע ץלמומ

                                                  :

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