Page 18 - Bio Rex NONI Booklet ENG

Potent physiological immune-stimulator with

distinctive cancer-preventive properties.

NONI’s cancer chemo-preventive effect has been

described in some thirty human and animal model

researches so far. The promotion of these clinical

studies was based on the large and solid body of over

300 scientific articles reporting laboratory evidences

on the immune-stimulating potency of NONI fruit,

namely of its rich anthraquinone and polyterpenoid

fractions. These families of active compounds, sensibly

concentrated in the preparation following fermentation

process, are able to affect the modulation of many

pathways distinctive of the human immune anticancer

function. A controlled clinical study on heavy smokers

has shown that NONI fruit consumption was able to

reduce DNA damage (adducts) in the peripheral blood

lymphocytes, a validated biomarker for the prediction

of environmental-driven cancer risk. A further

controlled clinical study was able to demonstrate a

consistent decrease of pain perception in advanced

cancer patients. NONI was also found effective in the

reduction of advanced gastric cancer in two published

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