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For regulators, this feature addresses a key safety hurdle.
For producers, it allows for controlled production with
minimal risk of cross-contamination or regulatory delay.

3. Oral Compatibility and Digestive Delivery

Lettuce is edible by nature—and that’s exactly what makes
it powerful as a delivery vehicle for orally administered
biologics.

The leafy structure offers:

• Natural encapsulation of the therapeutic protein
within the plant matrix
• Resistance to digestive enzymes, due to fibrous
cell walls that humans cannot easily break down
• Targeted release in the small intestine, where
mucosal immune tissues (e.g. Peyer’s patches)
reside

Rather than requiring synthetic coatings or complex
microencapsulation, lettuce delivers a protein protected
by its own cellular scaffolding, offering both stability and
site-specific exposure.

This isn’t just a cost saver. It’s immune design—ensuring
the protein reaches the part of the body that can respond
with tolerance rather than rejection.

4. Proven Track Record in Therapeutic Expression

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