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• The immunologic signature of the antigen as it
interacts with mucosal immune cells

This integration of pharmacology, formulation, and
immunology is not incremental.
It’s systemic—a way to build biologics that live within the
immune system, not in conflict with it.

From Synthetic Biology to Immuno-Synthetic
Engineering

This convergence is giving rise to a new discipline—what
might best be described as immuno-synthetic
engineering.

It’s not just about editing genes.
It’s about engineering immune relationships through:

• Controlled antigen exposure
• Strategic delivery contexts
• Durable immune education

In this model, the drug is not a blunt instrument—it’s a
biological conversation, shaped by:

• Where it is presented
• How it is folded
• What molecular signals surround it
• And how the immune system interprets its presence
over time

This is not plant biology.
This is regulatory immunology in physical form.

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