Page 9 - Orthofeed_Issue4_Feb2022

ORTHOFEED, Edition 4 08

absolute risk of the composite of deep-vein Thrombosis and Haemostasis; JBJS, The orthopedic, and urologic surgery. N Engl J Med. 1988;
Articles were then stratified into categories orthopaedic surgeons to navigate the 318(18):1162-1173.

based on clinical focus such as epidemiologic, complexities of venous thromboembolism and thrombosis, non-fatal pulmonary embolism, and Journal of Bone and Joint Surgery; Arch Int 7) Eriksson BI, Borris LC, Friedman RJ, Haas S, Huisman
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comparison, aspirin, asymptomatic DVT, Direct thromboprophylaxis across orthopaedic death from any cause by 9.2%. In this Med, The Archives of Internal Medicine) MV, Kakkar AK, Bandel TJ, Beckmann H, Muehlhofer E,

Thrombin Inhibitor, LMWH, mechanical, novel surgery. The Top 100 cited articles included in randomized controlled trial involving 2459 Misselwitz F, Geerts W; RECORD1 Study Group.
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Rivaroxaban versus enoxaparin for thromboprophylaxis
factor Xa Inhibitors, panel opinion, the final overall orthopaedic list generated a total patients undergoing hip arthroplasty, Conclusion after hip arthroplasty. N Engl J Med. 2008
6;358(26):2765-2775.
unfractionated heparin, and warfarin. 4 of 21,099 citations. The three articles amongst rivaroxaban showed a decrease in risk of major Thromboprophylaxis is one of the most crucial
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100 with highest citations are given in Figure 1. venous thromboembolism by 1.6% than aspect of orthopaedic surgery and remains at 8) Turpie AG, Haas S, Kreutz R, Mantovani LG, Pattanayak
CW, Holberg G, Jamal W, Schmidt A, van Eickels M,
enoxaparin. More recent studies have replicated the forefront of research and surgery Lassen MR. A non-interventional comparison of
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Most cited articles on DVT prophylaxis in
similar findings. Thus, factor Xa inhibitors are considerations. The present report presented a rivaroxaban with standard of care for thromboprophylaxis
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orthopedic surgery considered a viable alternative to low molecular favourable trend towards high impact research after major orthopaedic surgery in 17,701 patients with
propensity score adjustment. Thromb Haemost. 2014;
The present study primarily aimed to analyze weight heparins (LMWHs) in both ACCP and within orthopedic thromboprophylaxis. Studies 111(1):94-102.
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published literature and provide a toolkit for
American Academy of Orthopaedic Surgeons included in analysis were highly cited for a 9) Johanson NA, Lachiewicz PF, Lieberman JR, Lotke PA,
Parvizi J, Pellegrini V, Stringer TA, Tornetta P 3rd, Haralson
(AAOs) guidelines. 9, 10 multitude of factors like clinical significance, RH 3rd, Watters WC 3rd. American academy of
Highest cited Second most cited Third most cited study quality, and importance in orthopaedics orthopaedic surgeons clinical practice guideline on.
Prevention of symptomatic pulmonary embolism in
Top Journals publishing on DVT prophylaxis in research. Such studies improve our patients undergoing total hip or knee arthroplasty. J Bone
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The 8th edition of American Reduction In Fatal Rivaroxaban versus Joint Surg Am. 2009; 91(7):1756-1757.
College of Chest Physician Pulmonary-Embolism and enoxaparin for understanding about the ever-changing
(ACCP) Guidelines- Venous Thrombosis by thromboprophylaxis after orthopedic surgery:
‘Prevention of venous Perioperative Administration knee arthroplasty landscape of anticoagulation regimens as well 10) Falck-Ytter Y, Francis CW, Johanson NA, Curley C,
thromboembolism’, Of Subcutaneous Heparin - The top three journals with the greatest number Dahl OE, Schulman S, Ortel TL, Pauker SG, Colwell CW Jr.
Overview Of Results Of 4 Prevention of VTE in orthopedic surgery patients:
Randomized Trials of publications in the list of 100 (Figure 2) were: as DVT prophylaxis in orthopaedic surgery. Antithrombotic Therapy and Prevention of Thrombosis,
1) The Journal of Thrombosis and 9th ed: American College of Chest Physicians
Evidence-Based Clinical Practice Guidelines. Chest. 2012;
Haemostasis (impact factor: 4.662) References 141(2 Suppl):e278S-e325S.
Figure 1: The top three most cited articles on DVT prophylaxis in orthopedic surgery 4
2) The Journal of Bone and Joint Surgery 1) Warren JA, Sundaram K, Anis HK, Kamath AF, Higuera
(impact factor: 4.31) CA, Piuzzi NS. Have Venous Thromboembolism Rates
a) The highest cited article: general, orthopaedic, and urologic surgery 3) The Archives of Internal Medicine (JAMA) Decreased in Total Hip and Knee Arthroplasty? J
Arthroplasty. 2020; 35(1):259-264.
The 8th edition of American College of Chest (1988) captured some of the earliest high quality (impact factor: 20.77). 2) Flevas DA, Megaloikonomos PD, Dimopoulos L,

Physician (ACCP) Guidelines- Prevention of findings in orthopaedic thromboprophylaxis. 6 Mitsiokapa E, Koulouvaris P, Mavrogenis AF.
Thromboembolism prophylaxis in orthopaedics: an
venous thromboembolism published in Chest in update. EFORT Open Rev. 2018; 3(4):136-148.

2008 had a calculated citation density of 215.54 c) The third highest cited article:
3) Thompson DF, Walker CK. A descriptive and historical
of citations/year since publication. The most Rivaroxaban versus enoxaparin for review of bibliometrics with applications to medical
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sciences. Pharmacotherapy. 2015; 35(6):551-559
probable explanation for the high number of thromboprophylaxis after hip arthroplasty (2008)
citations of the ACCP guidelines is the broad, highlighted both the role of novel factor Xa 4) Sedani A, Yakkanti R, Allegra P, Mattingly L, Aiyer A.
Thromboprophylaxis across orthopaedic surgery:
multidisciplinary recommendations put forward inhibitors and the driving force of arthroplasty in Bibliometric analysis of the most cited articles. J Clin
Orthop Trauma. 2021; 23;16:157-167.
by the experts. 4 DVT literature. 7
5) Geerts WH, Bergqvist D, Pineo GF, Heit JA, Samama
CM, Lassen MR, Colwell CW. Prevention of venous
b) The second highest cited article: Rivaroxaban in thromboprophylaxis: thromboembolism: American College of Chest Physicians
Evidence-Based Clinical Practice Guidelines (8th Edition).
Reduction in fatal pulmonary embolism and The literature analysis demonstrated that Chest. 2008; 133(6 Suppl):381S-453S.
venous thrombosis by perioperative investigators have actively studied the efficacy
6) Collins R, Scrimgeour A, Yusuf S, Peto R. Reduction in
administration of subcutaneous heparin - of rivaroxaban in orthopaedic surgery. Figure 2: Top three journals with highest fatal pulmonary embolism and venous thrombosis by
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overview of results of randomized trials in Rivaroxaban has been found to reduce the percentage of articles (JTH, Journal of perioperative administration of subcutaneous heparin.
Overview of results of randomized trials in general,