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ORTHOFEED, Edition 4                                                                                 10

 absolute  risk  of  the  composite  of  deep-vein   Thrombosis  and  Haemostasis; JBJS,  The   orthopedic, and urologic surgery. N Engl J Med. 1988;
        318(18):1162-1173.
 thrombosis, non-fatal pulmonary embolism, and   Journal of  Bone and Joint Surgery;  Arch Int
 death  from  any  cause  by  9.2%.   In  this   Med, The Archives of Internal Medicine)  7) Eriksson BI, Borris LC, Friedman RJ, Haas S, Huisman
 7
        MV, Kakkar AK, Bandel TJ, Beckmann H, Muehlhofer E,
 randomized  controlled  trial  involving  2459   Misselwitz F, Geerts W; RECORD1 Study Group.
        Rivaroxaban versus enoxaparin for thromboprophylaxis
 patients   undergoing   hip   arthroplasty,   Conclusion  after hip arthroplasty. N Engl J Med. 2008

 rivaroxaban showed a decrease in risk of major   Thromboprophylaxis is one of the most crucial   6;358(26):2765-2775.
 venous  thromboembolism  by  1.6%  than   aspect  of  orthopaedic  surgery  and  remains  at   8) Turpie AG, Haas S, Kreutz R, Mantovani LG, Pattanayak
        CW, Holberg G, Jamal W, Schmidt A, van Eickels M,
 enoxaparin.  More recent studies have replicated   the   forefront   of   research   and   surgery   Lassen MR. A non-interventional comparison of
 7
 similar  findings.   Thus,  factor  Xa  inhibitors  are   considerations. The present report presented a   rivaroxaban with standard of care for thromboprophylaxis
 8
        after major orthopaedic surgery in 17,701 patients with
 considered a viable alternative to low molecular   favourable trend towards high impact research   propensity score adjustment. Thromb Haemost. 2014;
        111(1):94-102.
 weight  heparins  (LMWHs)  in  both  ACCP  and   within orthopedic thromboprophylaxis.   Studies
 4
 American  Academy  of  Orthopaedic  Surgeons   included  in  analysis  were  highly  cited  for  a   9) Johanson NA, Lachiewicz PF, Lieberman JR, Lotke PA,
        Parvizi J, Pellegrini V, Stringer TA, Tornetta P 3rd, Haralson
 (AAOs) guidelines. 9, 10  multitude  of  factors  like  clinical  significance,   RH 3rd, Watters WC 3rd. American academy of
        orthopaedic surgeons clinical practice guideline on.
 study  quality,  and  importance  in  orthopaedics   Prevention of symptomatic pulmonary embolism in
 Top Journals publishing on DVT prophylaxis in   research.    Such   studies   improve   our   patients undergoing total hip or knee arthroplasty. J Bone
 4
        Joint Surg Am. 2009; 91(7):1756-1757.
 orthopedic surgery:  understanding   about   the   ever-changing   10) Falck-Ytter Y, Francis CW, Johanson NA, Curley C,

 The top three journals with the greatest number   landscape  of  anticoagulation  regimens  as  well   Dahl OE, Schulman S, Ortel TL, Pauker SG, Colwell CW Jr.
 of publications in the list of 100 (Figure 2) were:  as DVT prophylaxis in orthopaedic surgery. 4  Prevention of VTE in orthopedic surgery patients:
        Antithrombotic Therapy and Prevention of Thrombosis,
 1)  The   Journal   of  Thrombosis   and   9th ed: American College of Chest Physicians
        Evidence-Based Clinical Practice Guidelines. Chest. 2012;
 Haemostasis (impact factor: 4.662)  References  141(2 Suppl):e278S-e325S.

 2)  The  Journal  of  Bone  and  Joint  Surgery   1) Warren JA, Sundaram K, Anis HK, Kamath AF, Higuera
 (impact factor: 4.31)  CA, Piuzzi NS. Have Venous Thromboembolism Rates
 a) The highest cited article:   general,  orthopaedic,  and  urologic  surgery   3) The Archives of Internal Medicine (JAMA)   Decreased in Total Hip and Knee Arthroplasty? J
 Arthroplasty. 2020; 35(1):259-264.
 The  8th  edition  of  American  College  of  Chest   (1988) captured some of the earliest high quality   (impact factor: 20.77).  2) Flevas DA, Megaloikonomos PD, Dimopoulos L,

 Physician  (ACCP)  Guidelines-  Prevention  of   findings in orthopaedic thromboprophylaxis. 6  Mitsiokapa E, Koulouvaris P, Mavrogenis AF.
 Thromboembolism prophylaxis in orthopaedics: an
 venous thromboembolism published in Chest in   update. EFORT Open Rev. 2018; 3(4):136-148.

 2008 had a calculated citation density of 215.54   c) The third highest cited article:
 3) Thompson DF, Walker CK. A descriptive and historical
 of  citations/year  since  publication.  The  most   Rivaroxaban   versus   enoxaparin   for   review of bibliometrics with applications to medical
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 sciences. Pharmacotherapy. 2015; 35(6):551-559
 probable  explanation  for  the  high  number  of   thromboprophylaxis after hip arthroplasty (2008)
 citations  of  the  ACCP  guidelines  is  the  broad,   highlighted  both  the  role  of  novel  factor  Xa   4) Sedani A, Yakkanti R, Allegra P, Mattingly L, Aiyer A.
 Thromboprophylaxis across orthopaedic surgery:
 multidisciplinary recommendations put forward   inhibitors and the driving force of arthroplasty in   Bibliometric analysis of the most cited articles. J Clin
 Orthop Trauma. 2021; 23;16:157-167.
 by the experts. 4  DVT literature. 7
 5) Geerts WH, Bergqvist D, Pineo GF, Heit JA, Samama
 CM, Lassen MR, Colwell CW. Prevention of venous
 b) The second highest cited article:   Rivaroxaban in thromboprophylaxis:   thromboembolism: American College of Chest Physicians
 Evidence-Based Clinical Practice Guidelines (8th Edition).
 Reduction  in  fatal  pulmonary  embolism  and   The  literature  analysis demonstrated  that   Chest. 2008; 133(6 Suppl):381S-453S.
 venous   thrombosis   by   perioperative   investigators  have  actively  studied  the  efficacy
 6) Collins R, Scrimgeour A, Yusuf S, Peto R. Reduction in
 administration  of  subcutaneous  heparin  -   of   rivaroxaban   in   orthopaedic   surgery.    Figure  2:  Top three  journals  with highest   fatal pulmonary embolism and venous thrombosis by
 3
 overview  of  results  of  randomized  trials  in   Rivaroxaban  has  been  found  to  reduce  the   percentage  of articles (JTH, Journal of   perioperative administration of subcutaneous heparin.
 Overview of results of randomized trials in general,
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