Page 149 - International Space Station Benefits for Humanity, 3rd edition.
P. 149

Karolinska Institute in Sweden, this research has been   effect in lung circulation. The drug widens the blood
               ongoing for more than 10 years, most recently within   vessels and counteracts life-threating increases of
               the Airway Monitoring experiments. These experiments   the local blood pressure.
               analyze the amount of nitric oxide exhaled by   On the moon and on Mars, astronaut’s lungs may
               astronauts under different conditions in the weightless   become easily irritated or inflamed by dust particles.
               environment of space (e.g., normal pressure, reduced   The reduced gravity on those celestial bodies makes
               pressure in an airlock, pre-/post-spacewalk etc.)
                                                               floating dust a real threat for humans.
               The astronauts breathe into a specially developed   Understanding the effects of weightlessness and
               instrument that measures nitric oxide levels.    reduced pressure on airway health will help space
               The purpose of taking reduced measurements in   explorers monitor, diagnose and treat lung inflammation
               an airlock—normally used to exit a spacecraft for   during spaceflight. This information is key to ensuring
               spacewalks, and is set at a 30% reduced pressure—   the health and safety of astronauts on longer missions
               is to simulate conditions in future habitats on Mars,    beyond Earth’s orbit.
               and is equivalent to being at 3000 m (9843 ft) altitude
               on Earth.
               The device that measures the nitric oxide is lightweight,   Bringing Space Station Ultrasound
               easy to use and accurate. The same instrument   to the Ends of the Earth
               is currently used in clinics and hospitals, helping   Fast, efficient and readily available medical attention is
               asthmatics and offering a quick and cheap way to
               diagnose lung problems. It was developed in close   key to survival in a health emergency. When a person
                                                               is stricken with injury or illness, getting a quick and
               collaboration between the medical technology industry   accurate diagnosis through medical imaging technology
               and the researchers at Karolinska Institute.
                B4H 3rd Edition                                can be crucial for ensuring proper treatment.
               In a similar collaboration with the pharmaceutical
               industry, the same researchers developed a nitric oxide-  For people who live in major cities and towns where
                                                               fully equipped hospitals are only a quick ambulance ride
               donating drug (Supernitro) with a uniquely selective
                                                               away, that is not usually a problem. However, for those
                                                               without medical facilities within easy reach, it can mean
                                                               the difference between life and death.
                                                               For astronauts in orbit about 386 kilometers
                                                               (240 miles) above Earth aboard the ISS, that
                                                               problem was addressed through the Advanced
               Measurable Monitoring                           Diagnostic Ultrasound in Microgravity (ADUM)
               Technology;                                     investigation. Space station astronauts are trained
               Immeasurable                                    to use a small ultrasound unit aboard the space
               Possibilities                                   station to examine fellow crew members. In the event
                                              Economic
                    Scientific
               Monitoring technology used to measure the       of a health concern, astronauts can use this unit to
                                                               diagnose many injuries and illnesses with the help of
                    Valuation
                                               Valuation
               fractionally exhaled nitric oxide (FeNO) content   doctors on Earth. Launched in 2011, the ultrasound
               produced by astronauts has led to a line of     unit used for ADUM was replaced with a smaller and
               commercial devices. Aerocrine’s NIOX MINO has   even more sophisticated scanner dubbed Ultrasound 2,
                                              ECONOMIC
                   SCIENTIFIC
               been used to complete more than 10 million tests   which is currently in use aboard the ISS.
                   VALUATION
                                              VALUATION
               since 2004, whereas NIOX VERO was introduced in
               2014. In 2015, Circassia Pharmaceuticals acquired
               Aerocrine for $214 million. In 2017, these NIOX
               devices were the leading point-of-care FeNO
               monitoring products, used to perform approximately   Space station astronauts are
               3.6 million tests annually in more than 8,700    trained to use a small ultrasound
               locations worldwide, with total sales of $35.9 million
               in 2017—an increase of 18% over 2016.            unit aboard the space station to
                                                                examine fellow crew members.
                 Human            Earth Observation        Innovative             Global            Economic
                  Health            and Disaster           Technology           Education          Development
                                     Response                                                        of Space
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