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        SCIENCEThursday 14 April 2016

Study: Brain implant lets paralyzed man regain use of hand 

MALCOLM RITTER                                                                                                                                                                                                                                                                                                                                                                hope to improve the tech-

AP Science Writer                                                                                                                                                                                                                                                                                                                                                             nology by such steps as

NEW YORK (AP) — A para-                                                                                                                                                                                                                                                                                                                                                       making the connections

lyzed 24-year-old man has                                                                                                                                                                                                                                                                                                                                                     wireless, perhaps placing

regained some use of his A28                                                                                                                                                                                                                                                                                                                                                  electrodes on or beneath
                                                                                                                                                                                                                                                                                                                                                                              the scalp rather than in
SCIENCEright hTahnudr, scdoanytr1o0llMinagrcith 2016
                                                                                                                                                                                                                                                                                                                                                                              the brain, and replacing
with signals relayed from
                                                                                                                                                                                                                                                                                                                                                                              the strapped-on forearm
electronic sensors in his
                                                                                                                                                                                                                                                                                                                                                                              electrodes with implanted
brain.
                                                                                                                                                                                                                                                                                                                                                                              ones.
Ian Burkhart of Dublin,
                                                                                                                                                                                                                                                                                                                                                                              Experts who weren’t in-
Ohio, can grasp a bottle,
                                                                                                                                                                                                                                                                                                                                                                              volved in the project said
pour its contents into a jar,
                                                                                                                                                                                                                                                                                                                                                                              the results hold promise.
pick up a stick and stir the
                                                                                                                                                                                                                                                                                                                                                                              Lee Miller of Northwestern
liquid. He can grab a cred-
                                                                                                                                                                                                                                                                                                                                                                              University, who has done
it card and swipe it through
                                                                                                                                                                                                                                                                                                                                                                              similar research in mon-
a reader. He can move in-
                                                                                                                                                                                                                                                                                                                          keys, called the results “an
dividual fingers and hold a                                                                                           Mars  mission                                                                    that  should                                                                          have
                                                                                                                                                                                                                                                                                                   launcheimdporbtanyt stenp”otowward de-
NASA salvagestoothbrush.                                                                                                                                                                                                                                                                                                                                                      veloping a tool for helping
But he can do these things
onlMy AfoRrCaIAfeDwUhNoNurs a week,                                                                                                                                                                                                                                                                                                                                           patients. He agreed that
ihnoao(CAAkAlPaPeP)bdAEoe—urraopCNtsoApAtraNoyScAAwea’VshnWEeRnrrAieeetexLx,trhpeeMrFiias-lars.                                                                                                                                                                                                                                                                               the forearm electrodes
memntisasilondeisvsitcillealtivhea.t inter-                                                                                                                                                                                                                                                                                                                                   would probably have to
preIntsstehaisdbroafinscsirganpaplsingantdhe                                                                                                                                                                                                                                                                                                                                  be implanted, but he said
                                                                                                                                                                                                                                                                                                                                                                              the current approach is

stimgurolautnedsehdis mMuascrsles InwSitighht                                                                                                                                                                                                                                                                                                                                 “clearly a good starting

elescptarocdeecsraoftn, hitshfeoreasprmac. e                                                                                                                                                                                                                                                                                                                                  point.”
WseiatfaWhorgcerehadneinm2cres0yps1hdr8ooalvpayeeumnittche’ashenn.tnsssoy,hsuotneorcetmien- dg                                                                                                                                                                                                                                                                                Chet Moritz of the Univer-
will eThveenrtoubaollyticaidlantdheer ewv-as                                                                          In this March 2016 photo provided by Ohio State University, Ian Burkhart plays a guitar video game                                                                                                                                                      sity of Washington called
erysduapypolivseeds otfopelifotploeffliktehis                                                                         as part of a study with neural bypass technology at The Ohio State University Wexner Medical                                                                                                                                                            the findings exciting. Direct
                                                                                                                      Center in Columbus.                                                                                                                                                                                                                                     stimulation of muscles can

                                                                                                                                                                                                                                          Associated Press

Burmkhoanrtth,with spinal cord freshman when he broke his Battelle Memorial Institute only a little sensation in his quickly lead to fatigue, he
injubriuets,enadneddpueprhsaidpeslinoetdh-in neck about six years ago. in Columbus, Ohio. He is arm because of his injury. noted, but that might be
berrsaekDwienceyitctinhFmejrumesatrnrynboc.aekhgreienborsysrtrstuaarmaidlueematnhktae. Ptinidcroeaj--                                                                                                                                                                                                                                                                         avoided by stimulating the
                                                                                                                      He dove into an ocean                                                            now at the Feinstein Insti-                                                           He also said his muscles tire                                                    spinal cord to move the
                                                                                                                      wave and was slammed                                                             tute for Medical Research                                                             after a while.                                                                   muscles instead.
                                                                                                                                                                                                       in Manhasset, New York.                                                               During the first few months,                                                     P. Hunter Peckham, a pro-
If avincde swhohueldn btehereddeesvigicneed into a sand bar. As a result,                                                                                                                              When Burkhart is in the lab,                                                          he became mentally worn
cainn tibmee. used at home, he is paralyzed from the
“it Mwailyl re20a1ll8y irnecprreeasesentsmtyhe middle of his chest down, a cable is attached to a out from concentrating on fessor of biomedical en-
quanelitxyt of laifveaailandbleindelpaeunnc- h with no use of his arms be- small projection from his exactly what muscles he gineering at Case West-
ids epelwnaavciunerenadr,cyl”oyhwztswea.tdioodOyBoMpeuvpaarekorrrshsr,tamubarnator,iistsswieetedhsojouoftsont                                                                                                                                                                                                                                                                 ern Reserve University in
                                                                                                                      low the elbow.                                                                   skull to carry signals from                                                           needed to move, he said.                                                         Cleveland, said the work is
                                                                                                                      For the experimental treat-                                                      the sensor to a comput-                                                               Now “it’s gotten much eas-                                                       valuable in showing that a
                                                                                                                                                                                                       er, which interprets what                                                             ier,” he said in an interview.
his tbhoedayli.gnment of Earth and ment, surgeons in 2014
Buriktshnaertig’shbocra. se is de- placed a tiny device on his movement he is trying to But if he faces a new task brain implant can be used
scrTibhedIniSnigahpt asppaecrereclreaaftseadims brain that includes 96 elec- accomplish. Then it sends or one he has not done for to control several muscles
WetdonsteusddyatyhebyinttheeriojrooufrnMaal rs trodes that penetrate just commands to an array a while, “I kind of have to at a time.
fNroammsbteuyonrredmseo.rseiIrletlsit’naesfgorrtchrndheteehelteeahdptaFetrtwosethintorhacepihsnpe.olrseTaerhtttisee-                                                                                                                                                                                                                                                          Peckham said many pa-
                                                                                                                      below the surface. It moni-                                                      of up to 160 electrodes                                                               think about it a little bit be-                                                  ralysis patients are already
                                                                                                                      tors a relatively small popu-                                                    strapped to his forearm.                                                              forehand, and really think                                                       doing “impressively well”
                                                                                                                                                                                                       Electrical stimulation from                                                           through what I’m trying to                                                       at home with a system that
pairnalyazevdacpueuomplechoapmebraetrein lation of brain cells in the                                                                                                                                  those electrodes activates                                                            accomplish.”
roboordticer atormms, eacsoumrepustuebrstle region that controls move-
                                                                                                                      mplWieTnhengidst nAotehufseghduiassaytric,2gM0thi1vat5irthcyaahrtn3i9sd,t’2ms,0sri1eall6inmo,dnNe-ArinSAgchilsspearsoih.dvaiidtn’esddshbaoyontNdinAgSfiAfno/grJaePLr2-0Cm1a8lutleas-cuhncdRthienepogzifactfthiasessthtaIeneiSdrIingaShBnitgudshrpktmahMcaoaerrrtecsrliafaslufnt.giddeeirtn-studmlyeintosgvetthhmeeeimnntAetrsssisotoirmcwoiuafitMltaheadtersPs.rieOhgsanns nadls
andgrouthnedr mdeoviecmesewntist.h sig-
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plalenatsk,iongr r.egThaein uosteheorf pmara-in                                                                                                                                                                                                                                                                                                                                  generated by other mus-
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signreaalsdyfrotomflyo.ther muscles                                                                                   drCoaplpifoinrngiao, wnillatakfeewovecrotnhe-                                    licseitecdontdos,blienkbinagckit toon ctohne-                                         Afrnoomtheear cNhAoSAtheMr.ars land-                                             orbaiptepr rofraocmh hcioguhldabboeveu.se-
theIty’sstiull nckonnotwronl. how much verersdaetisoignns, bbueiltdwinegenandthtoesset-                                                                                                                cpraetthe fomr aovleamunecnht,s,”nowsaiind                                            eBru—rkhtahrits osanied ahec’adr-slikzeed,to                                     Espuafruoclpeefcorrahfptaeisnopoirltebs itwaEixrtohpurenmsdsore
In cthoentratwsto, -tyheearnedwerlaeyporwt ill neinugroonfs thaendvawcueu’rme ctrhyainmg- D2r0.1A8l.i”Rezai, a study author wphaerteicleipdartoevers—omisesdcahyed-in theserevedreplainnjeutr.ies who can’t
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Burtkifhicargt oawlsasarea cocmolpleeglleing onbetheen parolojengc-tstwahnidleinagtgthoeal                                                                                                             oSrtabtuioznz,thnaott’ins gcothnasidt ehreedhaas                                      roRevesersaorcnhtehres sursfaaicde, atnhdey                                      scpohsllaeeircdict.ivgealyseksnaonwdnaalas nEdxoe-r

and the repair plans are of planetary scientists for scientific steppingstone for Odyssey, Mars Reconnais- Mars 2016.q
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