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b. If answer to sr. no. 1 against any principle, is 'no', please explain why: (tick up to 2 options) to sustainability throughout their lifecycle. shortness of breath caused by asthma and
Sr. Questions P1 P2 P3 P4 P5 P6 P7 P8 P9 1. (a) List of your products or services whose decrease the number of asthma attacks.
no. d e s i g n h a s i n c o r p o r a t e d s o c i a l o r Montelukast is also used before exercise to
1 The company has not understood environmental concerns, risks and/ or prevent breathing problems during exercise
(bronchospasm).
the principles. - - - - - - - - - opportunities. -
Montelukast Sodium is produced using an
2 The company is not at a stage where it The company continuously strives for sustainability
finds itself in a position to formulate and by strengthening the processes to minimize the improved process developed in the company's
implement the policies on specified environmental load, understanding risk to the R&D centre for the preparation of highly pure
principles. - - - - - - - - - environment and to human health arising from Montelukast sodium with high yield through
3 The company does not have financial or environment and promoting green processes by highly pure diol intermediate and Cyclopropyl
manpower resources available for the task. - - - - - - - - - strategic design of technologies and integrating Thio side chain compound. The process
with updated guidelines. involves the preparation of Montelukast Acid in
4 It is planned to be done within next solid form and nal stage Montelukast Sodium
6 months. - - - - - - - - - Following products help to address social or
by complete recovery of solvent under vacuum
5 It is planned to be done within the next environmental concerns in their design: to save solvent and prepare highly pure
1 year. - - - - - - - - - I. Loratadine & Desloratadine are antihistaminic Amorphous Montelukast Sodium as per
6 Any other reason (please specify). - - - - - - The company being - - drugs that reduces the effects of natural Morepen's own granted patent in US, Europe,

in pharmaceutical chemical histamine in the body. Histamine can Canada & India. The process is designed in
business, working produce symptoms of sneezing, itching, watery such as way so as to minimize the residual
in four corners of eyes, and runny nose. Loratadine is used to solvents and wastes. It is also having USFDA
applicable acts, treat sneezing, runny nose, watery eyes, hives, and CEP approval along with approval from
rules and policies.
Therefore, need for skin rash, itching, and other cold or allergy Chinese and Korean authority. Morepen is
formal policy has symptoms. further looking to enhance its process by
not been felt. Process of production of Loratadine chemically evaluating Biosynthetic pathways. Many
processes improvement related proposals
known as 8-chloro-11-(1-ethoxycarbonyl-4-
4. Governance related to BR 1. Does the policy relating to ethics, bribery and related to its cost reduction, reduction of BTC &
piperidylidene)-6, 11-dihydro-5H-benzo [5, 6]
corruption cover only the company? Yes / no.
a) Indicate the frequency with which the cycloheptal [1, 2B] pyridine has been recycling solvents is already in under
does it extend to the Group /Joint Ventures /
Board of Directors, Committees of the described. The process comprises reacting 2- implementation.
suppliers /Contractors /NGOs/ others?
Board or CEO to assess the BR perfor- Cyano-3-(3-chlorophenethyl) pyridine with N- III. Atorvastatin & Rosuvastatin are used along with
mance of the company. Within 3 months, Yes, the policy relating to ethics, bribery and Methyl-4-chloropyridine in cyclic aliphatic a proper diet to help lower "bad" cholesterol
3-6 months, annually, more than 1 year. corruption extends beyond our employees, both ether followed by cyclization & dehydration to and fats (such as LDL, triglycerides) and raise
Annually whole-time and independent directors and covers get N-Methyl Desloratadine which on reaction "good" cholesterol (HDL) in the blood. It
our subsidiary companies. The contracts with our with Ethyl chloroformate to give Loratadine by belongs to a group of drugs known as "statins."
b) Does the company publish a BR or a
suppliers, contractors and business partners conventional methods. This process provides It works by reducing the amount of cholesterol
sustainability report? What is the
include adherence to our principles concerning higher yields with desired quality of Loratadine made by the liver.
hyperlink for viewing this report? How
ethics. The company is also preparing a separate with minimum generation of waste.
frequently it is published? Atorvastatin calcium production includes
code of conduct being adhered to by its suppliers Desloratadine is the major metabolite of
The company's Annual Report includes Business and service providers. loratadine and the two drugs are similar in coupling of Diketone intermediate & Amino
Responsibility Report. The copy of the same is side chain to get deprotected Atorvastatin
2. How many stakeholder complaints have been safety and effectiveness. Desloratadine is which is deprotected in acid/ basic medium in
available on the website of the company i.e.,
received in the past nancial year and what available in many dosage forms and under aliphatic alcohol solvent followed by
www.morepen.com. percentage was satisfactorily resolved by the many trade names worldwide. The company purication and recrystallization to get
SECTION E: PRINCIPLE WISE PERFORMANCE management? If so, provide details thereof, in has USFDA and CEP approval for production of Crystalline Form I or Amorphous Atorvastatin
about 50 words or so. both the Drugs for sale in US and European
Principle 1: Ethics, Transparency and calcium by respective process designed in such
market.
Accountability The company encourages all its stakeholders to a way to minimize the residual solvents or
The company believes that while implementation of the freely share their concerns and grievances. The II. Montelukast sodium is a leukotriene (loo-koe- wastes. Also, Morepen is looking ahead
company has received nil complaints from various TRY-een) inhibitor. Leukotrienes are chemicals towards its technical collaboration with
minimum framework is a pre-requisite, superior
governance practices are vital for growing a stakeholders during the year 2020-2021. that human body releases when breathe in an Cambrex, Germany for development of various
allergen (such as pollen). These chemicals chemoenzymatic/biological methods for
sustainable and successful business. This has helped Principle 2: Product responsibility
cause swelling in your lungs and tightening of synthesis of Atorvastatin key intermediates
the company to gain the trust and condence of all its
Drug's product quality and safety are the fundamental the muscles around your airways, which can which are being currently imported from China.
stakeholders. The company has built its business
principles of the company. The company strives to result in asthma symptoms. Montelukast is used
practices on the three inviolable principles of ethics, These green chemistry initiatives will ultimately
provide goods and services that are safe and contribute regularly to prevent the wheezing and lead to eco-friendly industrial method for
transparency and accountability.