Page 438 - Feline Cardiology
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Generic Name    Indications/Drug   Dosage and   Comments                           Available sizes
               (Brand Name)    Type            Possible Routes
                                               of Admin.

               Torsemide       Loop diuretic   0.1–0.3 mg/kg   Similar effect to furosemide but more potent;   5, 10
               (Demadex [H],                   PO            produces diuretic effect similar to 1–3 mg/kg   20 mg
               torasemide)                     q 24h (or     furosemide, but may be less prone to   Tab
                                               divided       “braking effect” (diuretic resistance over time).   100 mg
                                               into q 12h)   May be considered when diuretic response to   Cap
                                                             high-dose furosemide is diminished, in   10 mg/ml
                                                             refractory heart failure. Some consider   Inj
                                                             decreasing the furosemide dose 50% when   HM
                                                             adding on, can always uptitrate. May cause
                                                             severe dehydration, so careful monitoring of
                                                             renal values, serum electrolytes, clinical
                                                             status, as for other loop diuretics.
               Valium—see
               Diazepam
               Vasopressin     Noncatecholamine   0.2–0.8 U/kg IV  Newer application in cardiac arrest-associated   20 U/ml
               (Pitressin [H])  vasoconstrictor              hypotension: may be similar to epinephrine   Inj
                               peptide                       for treatment of hypotension in this setting.   HM
                                                             Administer low dose and repeat as necessary
                                                             based on presence of pulse, blood pressure
                                                             monitoring (can repeat q 3–5 min, and can
                                                             alternate with epinephrine).

               Vasotec—see
               Enalapril
               Vasotop—see
               Ramipril
               Verapamil       Calcium-channel  0.05 mg/kg   Indicated for severe, uncontrolled   2.5 mg/ml
               (Calan,         blocker         slow          supraventricular tachycardias after correctable   Inj
               Isoptan,                        IV; may repeat  systemic causes have been addressed. Avoid   HM
               Verelan                         twice, 5–30   (or reduce dosage) if structural heart disease
               [all H])                        minutes       is present; risk of triggering congestive heart
                                               between       failure (or aggravating it, if already present) if
                                               doses         heart rate suppression is excessive; verapamil
                                                             is also a negative inotrope (contraindicated in
                                                             DCM and any other situation where
                                                             ventricular contractility is compromised). The
                                                             use of diltiazem IV has surpassed verapamil,
                                                             due to fewer negative inotropic effects with
                                                             diltiazem. Previous use as oral drug for feline
                                                             HCM has not persisted, likely due to absence
                                                             of demonstrated efficacy (like other drugs for
                                                             this disease) and greater ease of q 12–24 h
                                                             pilling with atenolol.

               Versed—see
               Midazolam
               Vetalar—see
               Ketamine                                                                                                 Drug Formulary
               Vetmedin—see
               Pimobendan
                                                                                                       Continued



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