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The elevated lactate (see Chapter 1) implies that the   intravenous fluids during the procedure rather than
             tissues are not receiving adequate oxygen/not able to   10 mL/kg/h. This led to fluid overload and pulmo-
  VetBooks.ir  utilize oxygen appropriately, consistent with   nary edema. The patient was treated with oxygen
                                                         support and intravenous furosemide and made a
             decreased perfusion, COHb, or cyanide toxicosis.
               At this point, you could perform co-oximetry (if
             available) to quantify the amount of COHb pre-  complete recovery.
             sent, which would be useful in differentiating
             COHb from cyanide toxicosis. However, since
             short-term provision of oxygen is unlikely to harm   Bibliography
             this patient and is the mainstay of treatment for   Auckburally, A. (2016) Pulse oximetry and oxygenation
             COHb toxicosis, high levels of O  should be pro-  assessment in small animal practice. In Practice 38,
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             vided to this patient to treat presumptive COHb   50–58.
             toxicosis even if co-oximetry is not available.   Boron, W. (2012) Transport of oxygen and carbon diox-
             Oxygen therapy helps to out-compete the CO for   ide in the blood. In: Boron, W., Boulpaep, E. (eds)
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             oxygen to the plasma portion of the bloodstream.  Missouri, USA, pp. 672–684.
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                                                            Simultaneous measurement of total hemoglobin and
             Case study 3: Post-operative SpO  drop         its derivatives in blood using co-oximeters: Analytical
                                          2                 principles; their application in selecting analytical
             A 6-month-old 3-kg miniature poodle undergoes a   wavelengths and reference methods; a comparision
             routine ovariohysterectomy at your clinic. During   of the  results of the  choices made.  Scandinavian
             recovery/extubation, the patient appears to be in   Journal of Clinical and Laboratory Investigation 56,
             respiratory distress and diffuse crackles are aus-  47-69.
             culted in all lung lobes.  The pulse oximeter   Chan,  E.,  Chan,  M.,  Chan,  M.  (2017)  Pulse  oximetry:
             throughout  the  procedure  read  98%,  but  now   understanding its basic principles facilitates appreci-
             reads 90% with a strong waveform that matches   ation  of  its  limitations.  Respiratory  Medicine  107,
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             her heart rate.                             Duke-Novakovski, T. (2017) Basics of monitoring equip-
             What  does  the  precipitous  drop  in the  pulse-ox   ment. Canadian Veterinary Journal 58, 1200–1208.
             reading from anesthesia to recovery indicate?  Gewib, H., Timm, U., Kraitl, J., et al. (2017) Non-invasive
               While under general anesthesia this patient was   multi wavelengths sensor system for measuring car-
             breathing  100%  oxygen,  which  should  cause  her   boxy- and methemoglobin.  Current Directions in
             PaO  to be between 400–500 mmHg. Her pulse-ox   Biomedical Engineering 3, 441–444.
                2
             will read 98–100% as long as the PaO  is >100 mmHg   Gracia, R., Shepherd, G. (2004) Cyanide poisoning and
                                         2
             (on the flat portion of the disassociation curve).   its treatment. Pharmacotherapy 24, 1358–1365.
             Therefore, it is possible that her lung function was   Hackett, T. (2002) Pulse oximetry and end tidal carbon
             decreasing throughout the procedure, but this was   dioxide monitoring.  Veterinary Clinics of North
             not detected until she was removed from oxygen and   America: Small Animal Practice 32, 1021–1029.
             placed back on room air since the pulse-ox reading   Herrmann, K., Haskins, S. (2005) Determination of P  for
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                                                            feline hemoglobin.  Journal of  Veterinary Emergency
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             in lung function while she was receiving 100% oxy-  Jubran,  A. (2004) Pulse oximetry.  Intensive Care
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             expected to fall below normal while breathing 100%   Mair, A., Taboada, F., Nitzan, M. (2017) Effect of lingual
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                          2
              2
             function lost) All possible causes of iatrogenic res-  in  anesthetized  dogs  and  cats.  Veterinary  Record
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             should be considered in this patient including but not   Marino, P.L. (2014) Systemic oxygenation. In: Marino, P.L.
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             resulting  in  the  patient  receiving  100  mL/kg/h  of   gas analysis, pulse oximetry, and end tidal carbon


             Pulse Oximetry                                                                   83
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