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reading, perform an arterial blood gas (see Chapter   Patients breathing supplemental oxygen should
            5). Patients who are cyanotic do not need to have   have pulse-ox readings that are >98%.  As men-
  VetBooks.ir  pulse  oximetry  performed  as  the  observer  has   tioned in Section 4.1, pulse oximetry no longer
                                                         correlates with PaO  once the PaO  is significantly
            already confirmed severe hypoxemia from visual
                                                                                    2
                                                                        2
            examination. At that moment, these patients need
                                                         surrogate for lung function outside of this range.
            emergent interventions, not exact measurements of   greater than 100 mmHg and cannot be used as a
            the degree of hypoxemia.                     Pulse oximetry values <95% indicate the need for
              Any patient undergoing heavy sedation or general   oxygen supplementation as they correlate with
            anesthesia should have continuous monitoring with   PaO  values less than 80 mmHg (i.e. hypoxemia).
                                                            2
            pulse oximetry. Patients who are heavily sedated to   Pulse oximetry can be inaccurate for a variety of
            anesthetized are at high risk of hypoxemia, hypoven-  reasons as discussed in the next section. Any abnor-
            tilation, or apnea for a variety of reasons. Continuous   mal result that does not fit with the patient’s pres-
            monitoring with pulse oximetry gives visual and audi-  entation or physical exam should be confirmed
            tory clues to the person monitoring anesthesia that   with an arterial blood gas analysis, as this is the
            desaturation is occurring and therefore can lead to   gold standard to diagnose hypoxemia. For more
            life-saving interventions. It is important to remember   information about interpretation of arterial blood
            that patients breathing high concentrations of oxygen   gas analysis, please see Chapter 5.
            are very far to the right on the flat portion of the
            OxyHb dissociation curve (see Fig. 4.3). As noted   4.5  Pitfalls of Pulse Oximetry
            in Section 4.1, these patients can experience signifi-
            cant loss of lung function and reductions in PaO    Multiple factors can affect the accuracy of pulse oxi-
                                                   2
            long before they reach the sigmoidal portion of the   metry in veterinary patients; these are outlined in
            curve and the pulse-ox will actually start to drop.   Table 4.2. In general, anything that interferes with the
            Therefore, a reliably dropping pulse-ox in a patient   pulse oximeter’s ability to detect an accurate pulsatile
            breathing supplemental oxygen should be taken as a   light signal may cause interference. Additional patient
            late indicator of a very serious oxygenation problem   factors that affect the accuracy of pulse oximetry are
            and immediately investigated.                the presence of abnormal species of Hb; pulse oxim-
                                                         etry cannot differentiate between MetHb, COHb, and
                                                         OxyHb. Interestingly, the application of gauze sponges
            4.4  Interpretation of Results
                                                         between the tongue and pulse-ox transmission probe
            Pulse oximetry values are reported as a percentage.   has actually been shown to improve SpO  readings in
                                                                                       2
            A normal SpO  in a patient breathing room air   both dogs and cats. It is hypothesized that the added
                        2
            (FiO  = 21%) is generally between 96–98%, which   thickness between the tongue and the LED and sensor
                2
            corresponds to a PaO  on the OxyHb dissociation   on the probe improves contact pressure.
                             2
            curve of 85–100 mmHg (see Fig. 4.2). Hypoxemia
            is defined as a PaO  less than 80 mmHg and severe
                           2
            hypoxemia  as  a  PaO   of  less  than 60  mmHg.   Hb alterations
                              2
            Therefore, patients with the correlating pulse-ox   It is important to remember that the pulse oximeter
            reading of <95% should be considered hypoxemic   is an approximation of the percentage of Hb in arte-
            and <90% severely hypoxemic.                 rial blood that is saturated with oxygen, NOT an
              The pulse oximeter is generally accurate within ±   approximation of the total arterial oxygen content.
            2–3% of the measured SaO  on an individual’s arte-  As outlined in  Box 4.1, severely anemic patients
                                 2
            rial blood gas but becomes less accurate with wors-  can have significantly low arterial oxygen content
            ening hypoxemia. In patients with a true SaO  <90%,   despite fully saturated Hb.
                                              2
            the pulse oximeter may vary by as much as ± 5%.   Similarly, the presence of a normal amount of
            Therefore, readings should be interpreted more as   oxygen in the blood does not guarantee that tissues
            trends within an individual patient and to classify   are adequately oxygenated. For example, cyanide
            general categories of hypoxemia rather than becom-  toxicosis inhibits oxidative phosphorylation inside
            ing fixated on a specific value. For example, a patient   the cell, preventing extraction of oxygen from the
            with a SpO  of 85% might actually be as low as 80%   blood into the cell. This will result in a high concen-
                     2
            or as high as 90%; either way, this patient is severely   tration of oxygen in both venous and arterial blood,
            hypoxemic and requires immediate intervention.  as none leaves to enter the tissues yet the tissues are

             80                                                            K.A. Marshall and A.C. Brooks
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