Page 90 - Basic Monitoring in Canine and Feline Emergency Patients
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underestimate  the  true  SaO   depending  on  the   does not fit with the measured pulse oximetry read-
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            patient’s clinical status. In this setting, a PaO  MUST   ing. Assuming the patient is not also severely ane-
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  VetBooks.ir  be measured to determine the amount of oxygen in   mic, she would be expected to be cyanotic at a SpO
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                                                         of 45% but her mucous membranes are pink.
            the plasma available to tissues. In order to defini-
                                                          Despite a heart rate that is ‘close’ to that of the
            tively diagnose MetHb, co-oximetry (discussed
            below) or a MetHb assay should be performed.  patient, the poor correlation with clinical signs
                                                         should make the practitioner consider this reading
                                                         erroneous. This does not automatically mean we can
            Co-oximetry
                                                         assume the patient is oxygenating well, simply that
            Certain pulse oximetry units have the ability to   we do not know her true level of oxygenation.
            measure abnormal Hb variants.  The sensors on   Repeating the reading on a different tissue bed, mak-
            these units emit the standard wavelengths of light   ing sure the probe is in place long enough to see good
            at 660 nm and 940 nm, but also emit two (or more)   signal quality, troubleshooting for issues such as out-
            additional wavelengths at 500 nm and 1400 nm.   lined in Table 4.2, or measurement of blood oxygena-
            These expanded wavelengths allow for the differ-  tion (PaO ) via arterial blood gas analysis could be
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            entiation  between  MetHb,  COHb,  OxyHb, and   considered in this patient to further assess whether or
            DeOxyHb. These units are commercially available,   not hypoxemia is the cause of these clinical signs.
            although not widely used.
              More commonly, co-oximetry is performed as
            part of arterial blood gas analysis, if the blood gas   Case study 2: SpO  in a house fire patient
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            analyzer has spectrophotometric capabilities.  To   A  3-year-old female spayed  domestic  shorthaired
            obtain the co-oximetry reading, the blood sample is   cat presents after being rescued from a house fire.
            hemolyzed  and  between  four  and  eight  different   Her vital signs are as follows: temperature 101.0°F
            wavelengths of light are projected through the sam-  (38.3°C), pulse 220 beats/minute, respiratory rate
            ple to measure OxyHb, DeOxyHb, COHb, and     60 breaths/minute, mucous membranes pink, capil-
            MetHb. The analyzer will typically display each as   lary refill time <2 seconds. She is obtunded and
            a % of the total Hb measured and calculate the   recumbent with increased respiratory effort. She
            percent oxygen saturation (SaO ).            has no obvious external burns but smells strongly
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                                                         of smoke. Her pulse-ox reads 98% with a strong
                                                         signal matching her heart rate.
            4.6  Case Studies                            Does this patient require supplemental oxygen?
                                                          Given her history of recently being in a house
            Case study 1: Do you trust this SpO  reading?
                                           2             fire, carbon monoxide, cyanide toxicity (commonly
            An 11-year-old female, spayed mixed breed dog   released from burning materials), and smoke inha-
            presents  for  increased  respiratory  rate  and  effort.   lation are all possible concerns. While primary lung
            On physical examination she is quiet, alert and   damage caused by smoke inhalation would nor-
            responsive, and is ambulatory with increased bron-  mally lower the SpO , this may be masked by arti-
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            chovesicular sounds bilaterally. Her vitals include a   ficial elevation of the SpO  caused by COHb or
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            temperature of 101.3°F (38.5°C), a heart rate of   cyanide toxicosis.
            190 beats/minute and a respiratory rate of 70   You perform a standard arterial blood gas and
            breaths/minute. Her mucous membranes are pink   find a pH of 7.3, a PaO  of 90 mmHg, PaCO  of
                                                                            2
                                                                                             2
                                                                                 −
            and moist.  Your assistant reports that they per-  32  mmHg,  bicarbonate (HCO ) of  15.2  mEq/L,
                                                                                 3
            formed a pulse oximetry measurement on your   base excess −9.9, and a SaO  of 96%. Lactate is
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            patient which revealed a SpO  of 45% and a heart   moderately elevated at 4.0 mg/dL.
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            rate of 180 beats/minute.                    Does this patient require supplemental oxygen?
            Do you believe this value? What would you do to   The normal PaO  tells you that the lungs are func-
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            troubleshoot to assess the accuracy of this value?  tioning well and severe compromise from smoke
              This is a significantly low SpO  reading, indicat-  inhalation is unlikely at this point in time (but should
                                      2
            ing very severe hypoxia barely compatible with life.   be reassessed over time). However, if this analyzer is
            This patient, while exhibiting signs consistent with   not performing co-oximetry, it  cannot differentiate
            respiratory distress (increased lung sounds and res-  OxyHb from COHb, so the SaO  given by the ana-
                                                                                  2
            piratory rate), is conscious and ambulatory which   lyzer may be confounded just like the pulse oximeter.
             82                                                            K.A. Marshall and A.C. Brooks
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