Page 1251 - Veterinary Toxicology, Basic and Clinical Principles, 3rd Edition

1182 Index

VetBooks.ir IM injection. See Intramuscular injection (IM Industrial chemicals, 127 129 International Agency for Research on Cancer
sample preparation for elemental analysis,
1121
injection)
(IARC), 12, 352, 1003
International Atomic Energy Agency (IAEA),
Imidacloprid, 202, 521
329 330
1,4-Imidazobenzodiazepine. See Flumazenil
Inflammation, 246, 248
Imidazolidine moiety, 521 522 Infertility, 526, 827 828 International Commission of Radiological
Imidazolines, 373 Inflammatory proteins, 448 Protection (ICRP), 332
Imidazolinones, 562 Infrared spectroscopy, 1071 International normalized ratio (INR), 584
herbicides, 554 Ingestion, 649, 905 906 International Programme on Chemical Safety
Immobilized pH gradient-isoelectric focusing, exposures, 389 (IPCS), 28
163 164 of petroleum by livestock, 661 662 Interstitial fibrosis, 370
Immune function, 769 Inhalation, 72 Interstitial nephritis, 370
Immune-mediated halothane hepatotoxicity botulism, 746 Intestinal barrier, 1047
mechanism, 253 254, 254f exposure, 323, 723 Intestinal microbiome, 109 110
Immunoassay, 85, 390, 397 studies, 323 Intoxication(s), 230, 719 720
Immunoglobulin (IgG), 795 Inhalation Toxicology Research Institute of birds and animals, 659
Immunosuppression, 262 (ITRI), 7 8 clinical signs, 850
Immunotoxic effects, 989 990 Inhaled sulfide, 484 diagnosing avian intoxications, 712
Immunotoxicant, 696 697 Inhibitory DREs (iDREs), 279 Intramuscular injection (IM injection), 201,
Immunotoxicity, 150, 150t, 976, 1022 Initiation, 250 403, 1150
IMPA. See Isopropyl-methylphosphonic acid Initiation-promotion-progression model, 344 Intranasal exposure, 323
(IMPA) Initiation promotion model, 342 Intraperitoneal injection (IP injection),
Impaired fertility in domestic animals, 298 Initiator, 342 1037 1038
Imperial Chemicals Incorporated Plant Inocybe spp., 960 Intratracheal instillation pharyngeal aspiration,
Protection Division (ICI Plant Inorganic 322
Protection Division), 585 analyses carbon nanotubes, 322
IMS. See Intermediate syndrome (IMS) cyanide, 1121 ultrafine particles, 322
In vitro cellular models, 151 ion chromatography, 1121 Intravenous (IV), 26, 201
In vitro exposures to nanomaterials, 321 322 nitrate/nitrite, 1121 atropine, 201
In vitro models of toxicity testing, 151 157 arsenicals, 411, 413 414 blockers, 491
endpoint determination for in vitro testing compounds, 51 catheter, 1142
systems, 153 157 fungicides, 573 574 fluids, 74
organization of tiered system for, 152f herbicides, 557 injection, 26
types of cell culture system, 151 153 materials, 569 570 lipid emulsion, 392
In vivo models in toxicity testing, 145 151 mercury, 455 456, 458 lipid infusion, 368, 390
animal models, 147t Mn, 445 Intravenous infusion of lipid emulsion (ILE),
carcinogenicity tests, 149 pentavalents, 412 547 548, 1154
cutaneous toxicity testing, 148 149 phosphorus, 1085 Intravenously CaEDTA (IV CaEDTA),
developmental toxicity testing, 148 Tl compounds, 623 624 441 442
genotoxicity testing, 149 Inositol phosphate (IP), 683 Intrinsic liver injury, 249
-3
immunotoxicity, 150, 150t INR. See International normalized ratio (INR) Iodate (IO ), 423
-1
neurotoxicity, 149 150 Insecta, 786, 787t Iodide (I ), 423
reproductive toxicity tests, 147 148, 148t Insecticide(s), 51 52, 234 235, 495, 525 Iodine, 330, 423 424
routes of test compound administration, cholinesterase inhibitors, 723 Iodine 131 ( 131 I), 327, 329
146 147, 148t CM, 496, 501 503 Iodized salt, 423 424
transgenic animals in toxicity testing, neonicotinoids, 724 Ion
150 151 OP, 495, 501 503 channels, 206 208
In vivo production of aflatoxins, 986 organochlorine, 720 723 chloride channels, 208
Increaser species, 852 pyrethrins/pyrethroids, 723 724 potassium channels, 207
Indanediones, 585, 587t Insects, 592, 786, 787t sodium channels, 206 207
chlorophacinone, 586 587 Institute for Game and Wildlife Research chromatography, 1121
diphacinone, 587 (IREC), 45 pair LC method, 599
Independent national procedures, 105 106 Institute of Laboratory Animal Resources source, 165
Indicator plants, 470 (ILAR), 20 trapping, 391
Indolizidine alkaloid swainsonine, 841 Institute of Toxicology and Forensic Sciences enhancing by excretion, 554
Inductively coupled plasma (ICP), 450, 460, (INTCF), 45 theory, 907
624 625 Intensive fluid therapy, 381 Ion exchange chromatography (IEX), 164
Inductively coupled plasma coupled optical Interactive theory, 472 Ionizing radiation, 327, 812
emission spectrometry (ICP-OES), Interagency Coordinating Committee on absorption, distribution, and accumulation of
1120, 1121f Validation of Alternative Methods radioactive contaminants, 329 330
sample preparation for elemental analysis, (ICCVAM), 153 154 acute effects of radiation exposure in
1121 Interleukin 1B (IL-1B), 222 animals, 330 332
Inductively coupled plasma-mass spectrometry Interleukin 6 (IL-6), 322 alpha particles, 327
(ICP-MS), 450, 460, 624 625, Intermediate syndrome (IMS), 505 beta particles, 327
1120 1121 Internal contamination, 329, 333 gamma rays, 327