Page 676 - Small Animal Internal Medicine, 6th Edition

648 PART IV Hepatobiliary and Exocrine Pancreatic Disorders

VetBooks.ir Drugs Used for Hepatobiliary and Pancreatic Disorders—cont’d INDICATIONS AND COMMENTS

DRUG NAME (TRADE NAME)
DOSAGE
Vitamins
Vitamin B 12 (cyanocobalamin) Dogs and cats—0.02 mg/kg Treatment of vitamin B 12 deficiency, particularly
IM, SC every 2-4 wk until associated with EPI and lack of pancreatic intrinsic
serum concentration factor
normalizes or oral doing
cyanocobalamin tablets:
0.25 mg once a day cats
and dogs 1-10 kg; 0.5 mg
once a day dogs >10-20;
1 mg once a day dogs body
weight >20 kg.
Vitamin K 1 (phytomenadione) See treatment of coagulopathy
section
Vitamin E See antioxidant section
Vitamin C (ascorbic acid) Cats and dogs oxidant Indicated only as supportive treatment for oxidant
toxins—30-40 mg/kg SC toxins affecting the liver (e.g., acetaminophen)
q6h for seven treatments Not indicated in other cases of hepatitis or copper
storage disease because increases absorption and
hepatic buildup of metals

APPT, Activated partial thromboplastin time; EPI, exocrine pancreatic insufficiency; GI, gastrointestinal; IM, intramuscular; IV, intravenous;
NK1, neurokinin 1; OSPT, one-stage prothrombin time; PO, by mouth; PSS, portosystemic shunt; SC, subcutaneous.