Page 784 - Small Animal Internal Medicine, 6th Edition

756 PART VI Endocrine Disorders

BOX 46.5
VetBooks.ir Some Potential Causes of Small Stature in Dogs and Cats Infectious diseases

Endocrine Causes
Congenital growth hormone deficiency Heavy intestinal parasitism
Congenital hypothyroidism Exocrine pancreatic insufficiency
Juvenile diabetes mellitus Hepatic disorders
Congenital hypoadrenocorticism Portosystemic vascular shunt
Hyperadrenocorticism Glycogen storage disease
Congenital (rare) Renal disease and failure
Iatrogenic Cardiovascular disease, anomalies
Skeletal dysplasia; chondrodystrophy
Nonendocrine Causes Mucopolysaccharidoses
Malnutrition Hydrocephalus
Gastrointestinal tract disorders
Megaesophagus
Inflammatory diseases

Failure to grow

History and
physical exam

Poor diet or History of Normal Abnormal Abnormalities involving
inadequate diarrhea and/or skeletal cardiovascular system
caloric intake vomiting conformation (e.g., murmur)

Make dietary Pursue Hypothyroidism Pursue
changes gastrointestinal Chondrodystrophy congenital
disorder/ cardiac anomaly
parasitism
Serum T , fT ,
4
4
and TSH tests
CBC, serum biochemistry panel, urinalysis

↑Liver enzymes,
Panhypo-
Azotemia, Hyperglycemia, proteinemia, Hypoalbuminemia, ↓BUN, glucose, and/or ↑Cholesterol ↑SAP, cholesterol, No abnormalities
isosthenuria, and/or cholesterol, and/or mild anemia isosthenuria, or
proteinuria Glucosuria No proteinuria No proteinuria hyposthenuria
Ammonium biurate
crystals
Liver function test
Pursue renal Diabetes mellitus Pursue gastro- Pursue Pursue hyper- Pursue congenital
disorder intestinal disease hypothyroidism adrenocorticism hyposomatotropism
Normal Abnormal (dwarfism)
1. Review diagnostic Portosystemic
evaluation vascular anomaly or
2. Consider renal or other hepatic disease
gastrointesinal

FIG 46.9
Diagnostic approach to the puppy or kitten that fails to grow. (From Feldman EC, Nelson
RW: Canine and feline endocrinology and reproduction, ed 3, St Louis, 2004, WB
Saunders.)