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CHAPTER 23 Cancer of the Gastrointestinal Tract 477
colostomy, improved outcomes have been achieved with defini- 21. Wallace J, Matthiesen DT, Patnaik AK: Hemimaxillec-
tive chemoradiation. The standard approach to therapy is con- tomy for the treatment of oral tumors in 69 dogs, Vet Surg 21:
337–341, 1992.
comitant RT and chemotherapy using 5-FU and mitomycin C.
VetBooks.ir Surgery is reserved for locally recurrent or persistent disease. The 22. Schwarz PD, Withrow SJ, Curtis CR, et al.: Mandibular resection
as a treatment for oral cancer in 81 dogs, J Am Anim Hosp Assoc
mean 5-year disease-free survival and overall survival rates are
27:601–610, 1991.
60% and 75%, respectively. Size and degree of invasion of the 23. Schwarz PD, Withrow SJ, Curtis CR, et al.: Partial maxillary resec-
primary tumor, regional LN involvement, and presence of dis- tion as a treatment for oral cancer in 61 dogs, J Am Anim Hosp Assoc
tant metastases are important prognostic factors. Identification of 27:617–624, 1991.
biomarkers that may serve as predictors of outcome or targets for 24. Sarowitz BN, Davis GJ, Kim S: Outcome and prognostic factors
therapy is being explored. following curative-intent surgery for oral tumours in dogs: 234
cases (2004 to 2014), J Small Anim Pract 58:146–153, 2017.
References 25. Bronden LB, Eriksen T, Kristensen AT: Oral malignant melano-
mas and other head and neck neoplasms in Danish dogs: data from
the danish veterinary cancer registry, Acta Vet Scand 51:54, 2009.
1. Patnaik AK, Liu SK, Hurvitz AI, et al.: Nonhematopoietic neo- 26. Richardson RC: Canine transmissible venereal tumor, Compend
plasms in cats, J Natl Cancer Inst 54:855–860, 1975. Contin Educ Pract Vet 3:951–956, 1981.
2. Hoyt RF, Withrow SJ: Oral malignancy in the dog, J Am Anim 27. Straw RC, LeCouteur RA, Powers BE, et al.: Multilobular osteo-
Hosp Assoc 20:83–92, 1984. chondrosarcoma of the canine skull: 16 cases (1978-1988), J Am
3. Dorn CR, Priester WA: Epidemiologic analysis of oral and pha- Vet Med Assoc 195:1764–1769, 1989.
ryngeal cancer in dogs, cats, horses and cattle, J Am Vet Med Assoc 28. Dernell WS, Straw RC, Cooper MF, et al.: Multilobular osteo-
169:1202–1206, 1976. chondrosarcoma in 39 dogs: 1979-1993, J Am Anim Hosp Assoc
4. Vos JH, van der Gaag I: Canine and feline oral-pharyngeal tumours, 34:11–18, 1998.
Zentralbl Veterinarmed A 34:420–427, 1987. 29. Farrelly J, Denman DL, Hohenhaus AE, et al.: Hypofractionated
5. Stebbins KE, Morse CC, Goldschmidt MH: Feline oral neoplasia: radiation therapy of oral melanoma in five cats, Vet Radiol Ultra-
a ten year survey, Vet Pathol 26:121–128, 1989. sound 45:91–93, 2004.
6. Dorn CR, Taylor DON, Frye FL, et al.: Survey of animal neoplasms 30. Iussich S, Maniscalco L, Di Sciuva A, et al.: PDGFRs expression in
in Alameda and Contra Costa Counties, California. I. Methodol- dogs affected by malignant oral melanomas: correlation with prog-
ogy and description of cases, J Natl Cancer Inst 40:295–305, 1968. nosis, Vet Comp Oncol 15:462–469, 2017.
7. Dorn CR, Taylor DON, Schneider R, et al.: Survey of animal 31. Smedley RC, Lamoureux J, Sledge DG, et al.: Immunohistochemi-
neoplasms in Alameda and Contra Costa Counties, California. II. cal diagnosis of canine oral amelanotic melanocytic neoplasms, Vet
Cancer morbidity in dogs and cats from alameda county, J Natl Pathol 48:32–40, 2011.
Cancer Inst 40:307–318, 1968. 32. Harvey HJ, MacEwen GE, Braun D, et al.: Prognostic criteria for
8. Cohen D, Brodey RS, Chen SM: Epidemiologic aspects of oral dogs with oral melanoma, J Am Vet Med Assoc 178:580–582, 1981.
and pharyngeal neoplasms in the dog, Am J Vet Res 25:1776–1779, 33. Hahn KA, DeNicola DB, Richardson RC, et al.: Canine oral
1964. malignant melanoma: prognostic utility of an alternative staging
9. Kudnig ST, Ehrhart N, Withrow SJ, et al.: Survival analysis of oral system, J Small Anim Pract 35:251–256, 1994.
melanoma in dogs, Vet Cancer Soc Proc 23:39, 2003. 34. William LE, Packer RA: Association between lymph node size and
10. Heyman SJ, Diefenderfer DL, Goldschmidt MH, et al.: Canine metastasis in dogs with oral malignant melanoma: 100 cases (1987-
axial skeletal osteosarcoma: a retrospective study of 116 cases (1986 2001), J Am Vet Med Assoc 222:1234–1236, 2003.
to 1989), Vet Surg 21:304–310, 1992. 35. Spangler WL, Kass PH: The histologic and epidemiologic bases
11. Ramos-Vara JA, Beissenherz ME, Miller MA, et al.: Retrospective for prognostic considerations in canine melanocytic neoplasia, Vet
study of 338 canine oral melanomas with clinical, histologic, and Pathol 43:136–149, 2006.
immunohistochemical review of 129 cases, Vet Pathol 37:597–608, 36. Sánchez J, Ramirez GA, Buendia AJ, et al.: Immunohistochemi-
2000. cal characterization and evaluation of prognostic factors in canine
12. Todoroff RJ, Brodey RS: Oral and pharyngeal neoplasia in the dog: oral melanomas with osteocartilaginous differentiation, Vet Pathol
a retrospective survey of 361 cases, J Am Vet Med Assoc 175:567– 44:676–682, 2007.
571, 1979. 37. Bergin IL, Smedley RC, Esplin DG, et al.: Prognostic evaluation of
13. Withrow SJ, Holmberg DL: Mandibulectomy in the treatment of Ki67 threshold value in canine oral melanoma, Vet Pathol 48:41–
oral cancer, J Am Anim Hosp Assoc 19:273–286, 1983. 53, 2011.
14. Withrow SJ, Nelson AW, Manley PA, et al.: Premaxillectomy in 38. Newman SJ, Jankovsky JM, Rohrbach BW, et al.: C-kit expression
the dog, J Am Anim Hosp Assoc 21:49–55, 1985. in canine mucosal melanomas, Vet Pathol 49:760–765, 2012.
15. White RAS, Gorman NT, Watkins SB, et al.: The surgical manage- 39. Smedley RC, Spangler WL, Esplin DG, et al.: Prognostic markers
ment of bone-involved oral tumours in the dog, J Small Anim Pract for canine melanocytic neoplasms: a comparative review of the liter-
26:693–708, 1985. ature and goals for future investigations, Vet Pathol 48:54–72, 2011.
16. Bradley RL, MacEwen EG, Loar AS: Mandibular resection for 40. Boston SE, Lu X, Culp WTN, et al.: Efficacy of systemic adjuvant
removal of oral tumors in 30 dogs and 6 cats, J Am Vet Med Assoc therapies administered to dogs after excision of oral malignant mel-
184:460–463, 1984. anomas: 151 cases (2001–2012), J Am Vet Med Assoc 245:401–407,
17. Salisbury SK, Richardson DC, Lantz GC: Partial maxillectomy and 2014.
premaxillectomy in the treatment of oral neoplasia in the dog and 41. Tuohy JL, Selmic LE, Worley DR, et al.: Outcome following
cat, Vet Surg 15(16), 1986. curative-intent surgery for oral melanoma in dogs: 70 cases (1998–
18. Salisbury SK, Lantz GC: Long-term results of partial mandibulec- 2011), J Am Vet Med Assoc 245:1266–1273, 2014.
tomy for treatment of oral tumors in 30 dogs, J Am Anim Hosp 42. Turrel JM: Principles of radiation therapy. In Thielen GH,
Assoc 24:285–294, 1988. Madewell BR, editors: Veterinary cancer medicine, ed 2, Philadel-
19. White RAS: Mandibulectomy and maxillectomy in the dog: long- phia, 1987, Lea & Febiger.
term survival in 100 cases, J Small Anim Pract 32:69–74, 1991. 43. Théon AP, Rodriguez C, Madewell BR: Analysis of prognostic
20. Kosovsky JK, Matthiesen DT, Marretta SM, et al.: Results of par- factors and patterns of failure in dogs with malignant oral tumors
tial mandibulectomy for the treatment of oral tumors in 142 dogs, treated with megavoltage irradiation, J Am Vet Med Assoc 210:778–
Vet Surg 20:397–401, 1991. 784, 1997.