Page 20 - Veterinary Laser Therapy in Small Animal Practice
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6                              Veterinary Laser Therapy in Small Animal Practice

                     are greenhouses green then? Probably because that’s   proteins. Combined, they can quite literally “hold”
                     more aesthetically pleasing to the eye. But in principle,   molecular oxygen (four molecules of O ). It is this iron
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                     a green-tinted glass would act like a filter of green light,   core that absorbs light very well, mostly because iron is
                     allowing through a greater proportion of what is left   a very heavy element compared to the organic chemis-
                     (white light minus the green), which would therefore   try (mostly carbon and oxygen) around it, and so it acts
                     be a more efficient illuminator of the chlorophyll.  as a nice contrast agent, especially in the near-infrared
                        Well, the same holds with melanin. Darker skin con-  close to its peak of absorption at 905 nm.
                     tains more melanin, which absorbs visible light more   Lastly, an enzyme called cytochrome c oxidase
                     strongly, and also, as it turns out, near-infrared light.   located on the membrane of the mitochondria inside
                     This is no accident. We have evolved skin to protect us   your cells absorbs near-infrared light. Much like hemo-
                     from the sun’s light. Again, it is no accident that the   globin, this enzyme absorbs principally because of its
                     majority  of  the  sun’s  light  is  in the  visible  and  near-  relatively heavy core of copper. Also like hemoglobin,
                     infrared range. In fact, only about 6% of the sun’s light   this enzyme “carries” molecular oxygen, but this time
                     is in the ultraviolet (UV) range. The reason we care so   within the cell as it works through the respiratory chain
                     much about this is that UV is ionizing light, meaning   in the process that produces adenosine triphosphate
                     that with a single photon it can break a chemical bond   (ATP), which the body uses as chemical energy.
                     and cause cellular damage, or worse, a genetic mutation.   More on what happens next – next, but by and large,
                     That is worse because if one of your cells dies, you have   that’s it. Nothing much else in the body absorbs enough
                     10,000,000,000,000 more to back it up. If one of your   light, at least the colors of light that can get inside the
                     cells mutates, however, that can lead to a whole mess of   body, strongly enough to do anything meaningful
                     altered cells that multiply faster than normal cells and   chemically. That makes things simpler to understand,
                     spread through the bloodstream to other places where   actually. The other keywords you’ll hear throughout the
                     they multiply further. This is called cancer.      book, things that clearly have a positive healing effect
                        But back to the infrared. We’ve evolved with    on individual cells and bulk tissue and were triggered by
                     melanin to protect us from sunlight, but that protec-  light, must have gotten their power from some process
                     tion wanes as you creep from the visible to the infra-  that these four targets started when they absorbed the
                     red, and by the time you get to about 900 nm and   light. So, what are some of those things?
                     greater, absorption by melanin disappears and the skin
                     is virtually invisible. So, for the shorter wavelengths,   As a veterinarian, I would like to say that there are
                     melanin acts like a barrier to light passing through the   some cells and molecules that ARE susceptible to
                     body, but as  wavelength increases, its effect becomes   light that doesn’t otherwise penetrate well into the
                     negligible.                                                    body. For example, we know that
                        Absorbers #1 (water) and #2 (melanin) absorb best           vitamin D synthesis depends on UV
                     on opposite sides of the spectrum: water on the longer         light incident on the skin. Some
                     wavelengths (> 950 nm) and melanin on the shorter              chemical compounds such as bilirubin
                     wavelengths (< 750 nm). This creates a valley in the   can lead to photosensitization. And of course, the
                     spectrum where the body is most transparent. Light in   cells in our retina transform light into electrical
                     this region can make it past the skin without burning a   impulses. But like he said, most of the effects in the
                     hole and into the body without “searing the meat.” For   cells come from these principal interactions.
                     that reason, we call it the “therapeutic window.”
                        Regardless of what other absorbers we talk about
                     next, their action outside this window is pretty much       1.4 Absorption leads to …
                     pointless, because even if their absorption led to the
                     growth of magic pixie dust in your cells, you really                 1.4.1 Heat
                     couldn’t get enough light there to initiate the magic.
                     Fortunately for us, targets #3 and #4 do in fact absorb   Heat is defined as the energy contained in a set of
                     well in this window.                               moving particles. So if anyone asks you how hot a
                        Hemoglobin is at the heart of red blood cells. It is   single particle is, you yell at them. Heat is collective
                     comprised of an iron core and four “claws” of folded   motion. Why would it be hard to believe, then, that










         REDONDO PRINT (4-COL BLEED).indd   6                                                                          08/08/2019   09:46
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