Page 51 - Veterinary Laser Therapy in Small Animal Practice

Tissue healing 37

Table 5.1 In vitro research on the potential antibacterial effects of red and infrared LT.

Dose (J/ Power Incubation
Microbial Wavelength cm or Power density CW/Hz time Results Reference Ref.
2
spp. (nm) (W) number
2
total J) (W/cm ) (h)
Nussbaum
3
1–80
810 60–360J 1–3 0.015 and CW? 20 more effect at 3 W and Krespi 2009 185
2
1–80 J/cm no effect
CW
2003
0.03
Decreased survival;
Total
181
24
940, 635
Staphylococcus aureus 630, 660, 810, 1–50 1.1 15 CW 20 increase at 50 J/cm 2 Nussbaum 183
higher doses
Non-significant
decrease at 5 J/
cm ; non-significant
2
2002
905
4074 and
2
9–10
870, 930
2009
3667
0.012 Around 5 CW 16–20 4074 J/cm kills 98% Bornstein 178
904 3 average, 2000 Hz 24, 48 Daily x 7 d over a Pereira 2014 186
colony. No effect
30 peak
Decreases growth
MRSA 940 + shock 1400 3 CW? 72 in combination with Krespi 2011 189
waves
shock waves
3.2 and 6.4 Mild decrease with
Strepto- coccus sanguis 632.8, 665, (632.8 nm); 0.003– CW? 48–96 marked with 665 and Chan 2003 184
632.8 nm; more
10.6 and 21
830
(665 and
0.1
830 nm
830 nm) 1–3 CW? 24 more effect at 3 W and Krespi 2009 181
Decreased survival;
Total
940, 635
Pseudomonas aeruginosa 810 60–360 J 3 0.015 and CW 20 W/cm inhibits growth Nussbaum 185
higher doses
1–20 J/cm with 0.03
2
1–80
2
2003
0.03
630, 660, 810,
2
905 1–50 1.1 15 CW 20 Decrease with 810 nm, Nussbaum 183
2002
5 J/cm
630, 660, 810, 1–50 1.1 0.015–0.03 CW 20 Increased growth with Nussbaum 183
20 J/cm and 0.03
2
905 W/cm 2 2002
Increased growth,
810 1–80 3 0.015–0.03 CW 20 especially at 0.03 W/ Nussbaum 185
2003
cm
2
Escherichia coli 940, 635 60–360 J 8–10 4.5 and 5.6 CW? 16–20 more effect at 3 W and Krespi 2009 178
Decreased survival;
Total
1–3
24
181
higher doses
Bornstein
2
4074 and
4074 J/cm (5.6 W/
870, 930
CW
2
cm ) kills 98%
3259
1300 nm increases
CW and growth; 950 nm at 26 2009
1300, 950 18–72 15 0.12 2,26,700, 1 Hz increases but at Karu 1990 182
1000 and
5000 Hz 5000 Hz decreases
growth
800
191
Tricho- phyton rubrum 870, 930 4074 and 0.005– 6.25 and 76 MHz 16–20 Decreased growth Manevitch 178
2010
0.14
Bornstein
10–11
100% killing
CW
4500
5.6
2009
Asper- gillus fumi- gatus 940, 635 60–360 J 1–3 CW? 24 Decreased survival; Krespi 2009 181
Total
effect at 3 W and
higher doses
Total
Candida albicans 940, 635 60–360 J 10–11 6.25 and CW? 16–20 Decreased survival; Krespi 2009 178
1–3
24
181
effect at 3 W and
higher doses
4074 and
Bornstein
CW
870, 930
100% killing
5.6
4500
Note: CW, continuous wave; MRSA, methicillin-resistant Staphylococcus aureus. 2009
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