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Urinary system (organa urinaria)   271




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                  12.24  Scanning electron microscope image of a transverse section of the renal medulla (dog; freeze fracture,
                  x3000).































                  12.25  Medulla (chicken). Haematoxylin and eosin stain   12.26  Medulla (chicken). Haematoxylin and eosin stain
                  (x40).                                         (x70).

                  Thin limb of loop of Henle                        The descending and ascending thin limbs are closely
                  The thin limb of the loop of Henle consists of simple squa-  apposed. This physical proximity facilitates the concentra-
                  mous epithelium. The width of the lumen is similar to that  tion of urine by establishing a counter-current system, in
                  of the proximal tubule (Figures 12.8 and 12.18) but the  conjunction with the surrounding capillaries and the col-
                  external diameter is reduced to around 12–15 μm. The cells  lecting duct system. In addition, the epithelial cells of the
                  lack a brush border, have relatively few organelles and lie  distal straight tubule (thick ascending limb of the loop of
                  immediately adjacent to surrounding capillaries.  Henle; see below) incorporate a basal labyrinth containing
                                                                                              +
                     The thin limb of the loop of Henle serves primarily to  ion pumps that actively transport Na  and Cl  out of the
                                                                                                     –
                  reabsorb water and concentrate the primary urine. The  cell into the interstitium. The distal straight tubule is rela-
                  extent to which this occurs is determined by the length  tively impermeable to water. Consequently, the osmolarity
                  of the loop. Desert rodents have particularly long-looped  of the interstitium gradually increases towards the renal
                  nephrons and extensively developed medullary zones, to  papilla. Driven by this mechanism, water passes through
                  minimise excretion of water in the urine.      the epithelium of the thin portion of the loop of Henle









       Vet Histology.indb   271                                                                                  16/07/2019   15:04
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