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1114  Section 10  Renal and Genitourinary Disease

            (a)                                     (b)                         (c)
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            (d)                         (e)                         (f)
















            Figure 122.6  Radiographic images of antegrade urethral catheterization for urethral tear in a cat. (a) The initial retrograde urethrogram
            showing severe contrast extravasation throughout the pelvic canal consistent with urethral rupture during attempted urethral
            catheterization. (b) Percutaneous access to the bladder has been obtained with an 18‐gauge over‐the‐needle catheter and iodinated
            contrast has been delivered to highlight the urinary bladder. (c) A hydrophilic guidewire is then advanced through the catheter and into
            the urinary bladder. (d) The wire is manipulated under fluoroscopic guidance and advanced antegrade out the urethra. As the tear was
            made during retrograde catheterization, the soft wire will follow the normal urethral lumen and pass out the penile urethra. (e) Once the
            wire is exteriorized, an open-ended urinary catheter can be advanced over the wire and will follow the true urethral lumen. Once the
            urinary catheter is within the bladder, the wire and bladder catheter are removed. (f) After seven days of in‐dwelling urethral
            catheterization, a repeat urethrogram shows the urethral tear has healed and the urinary catheter is removed.


            olemia. This can be achieved by at least matching the   kg IV/IM/SC or 0.5 mg/kg PO) can provide adequate seda­
            fluid rate to hourly urine production (even though the   tion to decrease stress and agitation, so long as the patient
            resultant rate could be very high). In the postobstructive   is stable. Given the potential functional nature of feline
            period there is also the potential concern for inadequate   UO, the alpha‐antagonist effects of acepromazine might
            urine production (<1 mL/kg/h). Major concerns in this   promote  urethral  relaxation  and  decrease  risk  of  reob­
            setting would be obstruction of the collection system,   struction once the urinary catheter is removed.
            dehydration, or oliguria from acute kidney injury.  Another important consideration is whether UO
             The obstructive process and urethral catheter place­  patients should be placed on antibiotics after catheter
            ment are painful and stressful, and could add to postob­  placement. This may be done with concern for existing
            structive morbidity. As such, provision of adequate   UTI, or for introducing a UTI secondary to catheter
            analgesia and sedation is also important for managing   placement. For cats, it has traditionally been accepted
            these patients. For cats, buprenorphine (0.01–0.02 mg/kg   that the incidence of bacterial infection in lower urinary
            q8h) generally provides sufficient pain control. If buprenor­  tract disease is very low. There is also evidence that pro­
            phine is not sufficient, a fentanyl continuous rate infusion   phylactic antibiotics do not prevent development of
            (CRI) (2–4 μg/kg/h) or intermittent methadone (0.2–  catheter‐associated UTI. Therefore, antibiotic therapy is
            0.3 mg/kg q6h) is recommended. Because of the potential   not recommended for UO in cats while the urinary cath­
            to cause excitability and hyperthermia, hydromorphone is   eter is in place unless bacteriuria and pyuria are docu­
            typically avoided. For dogs, fentanyl or methadone (similar   mented. Dogs with evidence of UTI (based on urine
            doses as cats) or hydromorphone (0.05–0.1 mg/kg) typi­  cytology or positive culture) should be placed onto
            cally provide adequate analgesia. Acepromazine (0.05 mg/  appropriate antibiotics.
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