Page 114 - Veterinary Immunology, 10th Edition
P. 114

enzyme release from neutrophils and thromboxane release from
  VetBooks.ir  macrophages, and regulates some T cell responses (Fig. 4.13). The

               other small complement peptide, C3a, can kill bacteria such as E.
               coli, Pseudomonas aeruginosa, Enterococcus faecalis, and Streptococcus

               pyogenes. C3a acts like other antimicrobial peptides by disrupting
               bacterial membranes. (C3a and C5a are also called anaphylatoxins
               since, when injected in sufficient amounts, they can kill an animal
               in a manner similar to anaphylaxis [Chapter 30].)




























                             FIG. 4.13  Some of the biological consequences of complement
                                                       activation.










































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