Page 157 - Veterinary Immunology, 10th Edition
P. 157
initiate adaptive immunity by processing antigens. They also act as
VetBooks.ir sentinel cells and initiate tissue repair. Unlike neutrophils, which
are specialized for a single task—the killing of invading organisms
—macrophages are much more flexible. Depending on their
location and environmental signals, macrophages can respond in
many different ways. The use of two phagocytic cell systems also
permits cooperation between neutrophils and macrophages to
enhance many aspects of innate immunity. For example,
neutrophils tend to be of greater importance in killing extracellular
pathogens, whereas macrophages dominate in the fight against
intracellular pathogens.
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